Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | GFER | P55789 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | ACACB | O00763 | 1/20 | 0.44 |
| ▸ | ACACA | Q13085 | 1/20 | 0.44 |
| ▸ | MAP2 | P11137 | 2/20 | 0.42 |
| ▸ | GPR35 | Q9HC97 | 4/20 | 0.40 |
| ▸ | PRKAB2 | O43741 | 1/20 | 0.39 |
| ▸ | PRKAG1 | P54619 | 1/20 | 0.39 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.39 |
| ▸ | PRKAA1 | Q13131 | 1/20 | 0.39 |
| ▸ | PRKAG3 | Q9UGI9 | 1/20 | 0.39 |
| ▸ | PRKAG2 | Q9UGJ0 | 1/20 | 0.39 |
| ▸ | PRKAB1 | Q9Y478 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5212831 | 0.96 | ACACB (0.44) | KDM4EALDH1A1HPGDMEN1HTT | |
| SCHEMBL5212633 | 0.87 | ALDH1A1 (0.49) | KDM4EALDH1A1HPGDMEN1HTT | |
| SCHEMBL5343866 | 0.81 | GPR35 (0.48) | ACACBACACAGPR35MAPK1 | |
| SCHEMBL5273891 | 0.78 | KDM4E (0.51) | KDM4EALDH1A1HPGDMEN1HTT | |
| SCHEMBL5269262 | 0.76 | JAK2 (0.51) | KDM4EALDH1A1HPGDMEN1HTT | |
| SCHEMBL5270466 | 0.75 | GPR35 (0.48) | ACACBACACAGPR35MAPK1 | |
| SCHEMBL5204577 | 0.74 | PTGES (0.39) | ACACBACACAGPR35GABRA1GABRG2 | |
| SCHEMBL5273364 | 0.74 | KDM4E (0.44) | KDM4EALDH1A1HPGDMEN1HTT | |
| SCHEMBL5270273 | 0.74 | MAP2 (0.55) | KDM4EALDH1A1HPGDMEN1HTT | |
| SCHEMBL5299189 | 0.74 | PTGES (0.52) | KDM4EALDH1A1HPGDMEN1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1778632-A1 | INDOLES USEFUL IN THE TREATMENT OF INFLAMMATION | Biolipox AB (SE) | 2007-05-02 | — | — | EP | disclosed |
| WO-2005123673-A1 | INDOLES USEFUL IN THE TREATMENT OF INFLAMMATION | BIOLIPOX AB (SE) | 2005-12-29 | — | — | WO | disclosed |