Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 3/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | PTGES | O14684 | 1/20 | 0.40 |
| ▸ | PRNP | P04156 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.39 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.39 |
| ▸ | RELA | Q04206 | 1/20 | 0.39 |
| ▸ | PARP1 | P09874 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | MKNK1 | Q9BUB5 | 2/20 | 0.38 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.38 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5717813 | 0.84 | RAB9A (0.56) | RAB9AL3MBTL1LMNAMAPTPTGES | |
| SCHEMBL9911965 | 0.72 | MAPT (0.47) | RAB9AL3MBTL1MAPTPRNPGAA | |
| SCHEMBL445286 | 0.69 | EHMT2 (0.53) | RAB9ALMNAMAPTGAASMN1; SMN2 | |
| SCHEMBL13341596 | 0.68 | RAB9A (0.55) | RAB9AL3MBTL1MAPTPTGESSMN1; SMN2 | |
| SCHEMBL30440577 | 0.66 | SRC (0.51) | LMNAGAAPARP1MKNK1CHEK2 | |
| Biphenyl SCHEMBL7707456 | 0.65 | KDM4E (0.52) | RAB9AL3MBTL1LMNAMAPTGAA | |
| Biphenyl SCHEMBL27350250 | 0.65 | BCAT2 (0.52) | RAB9AL3MBTL1LMNAMAPTGAA | |
| Biphenyl SCHEMBL9843146 | 0.65 | KDM4E (0.52) | RAB9AL3MBTL1LMNAMAPTGAA | |
| SCHEMBL18323991 | 0.65 | MEN1 (0.62) | LMNAMAPTGAAKDM4E | |
| SCHEMBL6885681 | 0.64 | RAB9A (0.54) | RAB9AL3MBTL1MAPTSMN1; SMN2NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1363925-B8 | MACROLIDE ANTIBIOTICS | GLAXO GROUP LTD (GB) | 2007-04-25 | — | — | EP | disclosed |
| EP-1363925-A1 | MACROLIDE ANTIBIOTICS | GLAXO GROUP LIMITED (GB) | 2003-11-26 | — | — | EP | disclosed |
| WO-2002050091-A1 | MACROLIDE ANTIBIOTICS | GLAXO GROUP LIMITED (GB) | 2002-06-27 | — | — | WO | disclosed |