Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.47 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | MGLL | Q99685 | 1/20 | 0.44 |
| ▸ | CXCL12 | P48061 | 1/20 | 0.41 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | PARP1 | P09874 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | BLM | P54132 | 1/20 | 0.38 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4884474 | 0.83 | FFAR1 (0.61) | MAPTHSD17B10FFAR1SMN1; SMN2HPGD | |
| SCHEMBL1170312 | 0.78 | FFAR1 (0.68) | MAPTHSD17B10FFAR1SMN1; SMN2CXCL12 | |
| Urea SCHEMBL27863158 | 0.77 | HPGD (0.67) | MAPTHSD17B10FFAR1SMN1; SMN2HPGD | |
| Hydrochloric Acid SCHEMBL3043801 | 0.77 | FFAR1 (0.65) | MAPTHSD17B10FFAR1SMN1; SMN2CXCL12 | |
| Carbamic Acid SCHEMBL27979510 | 0.75 | HPGD (0.63) | MAPTHSD17B10FFAR1SMN1; SMN2HPGD | |
| SCHEMBL2327183 | 0.73 | ALPI (0.39) | MAPTHSD17B10FFAR1SMN1; SMN2HPGD | |
| SCHEMBL21367554 | 0.73 | ALPI (0.39) | MAPTHSD17B10FFAR1SMN1; SMN2HPGD | |
| SCHEMBL1395738 | 0.72 | ALDH1A1 (0.57) | MAPTHSD17B10FFAR1SMN1; SMN2HPGD | |
| SCHEMBL5204601 | 0.72 | RAB9A (0.47) | MAPTHSD17B10SMN1; SMN2RAB9APOLB | |
| SCHEMBL445286 | 0.72 | EHMT2 (0.53) | MAPTHSD17B10SMN1; SMN2HPGDRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8198020-B2 | Contacting target cell or noncellular molecular entity with phagocytic marker and moiety that binds to a component that is present on or at surface of target cell or noncellular molecular entity, thereby increasing level or density of phagocytic marker on target cell; marker comprises phosphatidylserine | POTENTIA PHARMACEUTICALS, INC. (US) | 2012-06-12 | — | — | US | disclosed |