Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB1 | P08588 | 18/20 | 0.54 |
| ▸ | ADRB3 | P13945 | 18/20 | 0.54 |
| ▸ | ADRB2 | P07550 | 17/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5207745 | 0.92 | ADRB1 (0.46) | ADRB1ADRB3ADRB2KDM4EGAA | |
| SCHEMBL5206957 | 0.88 | ADRB3 (0.51) | ADRB1ADRB3ADRB2KDM4EGAA | |
| SCHEMBL5203201 | 0.88 | ADRB3 (0.42) | ADRB1ADRB3ADRB2KDM4EGAA | |
| SCHEMBL5203113 | 0.83 | ADRB1 (0.40) | ADRB1ADRB3ADRB2KDM4EGAA | |
| SCHEMBL5206634 | 0.80 | CYP3A4 (0.44) | ADRB1ADRB3ADRB2KDM4EGAA | |
| SCHEMBL6953116 | 0.79 | ADRB1 (0.56) | ADRB1ADRB3ADRB2KMT2A | |
| SCHEMBL7473303 | 0.79 | ADRB3 (0.58) | ADRB1ADRB3ADRB2 | |
| SCHEMBL6073654 | 0.78 | ADRB1 (0.62) | ADRB1ADRB3ADRB2KMT2A | |
| SCHEMBL6801052 | 0.77 | ADRB3 (0.59) | ADRB1ADRB3ADRB2 | |
| SCHEMBL7469736 | 0.77 | ADRB3 (0.53) | ADRB1ADRB3ADRB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1242083-B1 | PHENOXYPROPANOLAMINES, METHOD FOR PRODUCING THEM AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | SANOFI AVENTIS (FR) | 2007-03-14 | — | — | EP | claimed |
| EP-1242083-B1 | PHENOXYPROPANOLAMINES, METHOD FOR PRODUCING THEM AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | SANOFI AVENTIS (FR) | 2007-03-14 | — | — | EP | disclosed |
| US-6867220-B2 | Phenoxypropanolamines, method for producing them and pharmaceutical compositions containing them | SANOFI-SYNTHELABO (FR) | 2005-03-15 | — | — | US | disclosed |
| US-20030040530-A1 | Phenoxypropanolamines, method for producing them and pharmaceutical compositions containning them | SANOFI-AVENTIS (FR) | 2003-02-27 | — | — | US | disclosed |
| EP-1242083-A1 | PHENOXYPROPANOLAMINES, METHOD FOR PRODUCING THEM AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | Sanofi-Aventis (FR) | 2002-09-25 | — | — | EP | disclosed |
| WO-2001043744-A1 | PHENOXYPROPANOLAMINES, METHOD FOR PRODUCING THEM AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | SANOFI-SYNTHELABO (FR) | 2001-06-21 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030040530-A1 | Phenoxypropanolamines, method for producing them and pharmaceutical compositions containning them | CNR1, CORO1C, CBR1 | ADRB1 16/4885ADRB3 8/4885ADRB2 18/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.