Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB3 | P13945 | 11/20 | 0.53 |
| ▸ | ADRB1 | P08588 | 10/20 | 0.53 |
| ▸ | ADRB2 | P07550 | 9/20 | 0.52 |
| ▸ | MAPT | P10636 | 4/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6953116 | 0.84 | ADRB1 (0.56) | ADRB3ADRB1ADRB2LMNA | |
| SCHEMBL7473303 | 0.84 | ADRB3 (0.58) | ADRB3ADRB1ADRB2LMNA | |
| SCHEMBL6944610 | 0.82 | ADRB3 (0.53) | ADRB3ADRB1ADRB2MAPTALDH1A1 | |
| SCHEMBL6951393 | 0.82 | ADRB1 (0.57) | ADRB3ADRB1ADRB2 | |
| SCHEMBL6945509 | 0.79 | ADRB1 (0.58) | ADRB3ADRB1ADRB2MAPTLMNA | |
| SCHEMBL7473044 | 0.79 | ADRB3 (0.52) | ADRB3ADRB1ADRB2MAPTALDH1A1 | |
| SCHEMBL7469004 | 0.79 | ADRB3 (0.52) | ADRB3ADRB1ADRB2MAPTALDH1A1 | |
| SCHEMBL5204833 | 0.77 | ADRB1 (0.54) | ADRB3ADRB1ADRB2 | |
| SCHEMBL6953354 | 0.75 | ADRB1 (0.55) | ADRB3ADRB1ADRB2LMNA | |
| SCHEMBL6303828 | 0.74 | HRH3 (0.40) | ADRB3ADRB1ADRB2MAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1087961-B1 | PHENOXYLPROPANOLAMINES, METHOD FOR THE PRODUCTION THEREOF AND PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME | SANOFI SYNTHELABO (FR) | 2002-08-14 | — | — | EP | disclosed |