Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB3 | P13945 | 18/20 | 0.51 |
| ▸ | ADRB1 | P08588 | 11/20 | 0.45 |
| ▸ | ADRB2 | P07550 | 9/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5204833 | 0.88 | ADRB1 (0.54) | ADRB3ADRB1ADRB2KDM4EGAA | |
| SCHEMBL5203201 | 0.88 | ADRB3 (0.42) | ADRB3ADRB1ADRB2KDM4EGAA | |
| SCHEMBL5207745 | 0.84 | ADRB1 (0.46) | ADRB3ADRB1ADRB2KDM4EGAA | |
| SCHEMBL7246049 | 0.82 | ADRB3 (0.54) | ADRB3ADRB1ADRB2 | |
| SCHEMBL5206634 | 0.81 | CYP3A4 (0.44) | ADRB3ADRB1ADRB2KDM4EGAA | |
| SCHEMBL5203113 | 0.80 | ADRB1 (0.40) | ADRB3ADRB1ADRB2KDM4EGAA | |
| SCHEMBL6074507 | 0.80 | ADRB3 (0.64) | ADRB3ADRB1ADRB2 | |
| SCHEMBL5204459 | 0.80 | ADRB3 (0.47) | ADRB3ADRB1ADRB2 | |
| SCHEMBL6074795 | 0.79 | ADRB3 (0.56) | ADRB3ADRB1ADRB2 | |
| SCHEMBL6074614 | 0.76 | ADRB3 (0.60) | ADRB3ADRB1ADRB2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1242083-B1 | PHENOXYPROPANOLAMINES, METHOD FOR PRODUCING THEM AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | SANOFI AVENTIS (FR) | 2007-03-14 | — | — | EP | claimed |