SCHEMBL5204906

SCHEMBL5204906

CCC/C=C/c1[c]cccc1Cl

nearest known ligand 0.33

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
TLR8 Q9NR97 1/20 0.33
TYMP P19971 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5204914 1.00 TLR8 (0.33) TLR8TYMP
SCHEMBL5207607 0.89 L3MBTL1 (0.34)
SCHEMBL5207595 0.89 L3MBTL1 (0.34)
SCHEMBL20604271 0.72 TLR8 (0.45) TLR8
SCHEMBL20604275 0.72 TLR8 (0.45) TLR8
SCHEMBL27295154 0.70 TLR8 (0.37) TLR8TYMP
SCHEMBL294594 0.70 TLR8 (0.37) TLR8TYMP
SCHEMBL614577 0.70 TLR8 (0.37) TLR8TYMP
SCHEMBL8728518 0.70 TLR8 (0.35) TLR8TYMP
SCHEMBL8728515 0.70 TLR8 (0.35) TLR8TYMP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0980867-B1 KETONE DERIVATIVES AND MEDICINAL USE THEREOF TORAY INDUSTRIES (JP) 2007-08-08 EP disclosed
US-6100292-A Ketone derivatives and their medical applications TORAY INDUSTRIES, INC. (JP) 2000-08-08 US disclosed
EP-0980867-A1 KETONE DERIVATIVES AND MEDICINAL USE THEREOF TORAY INDUSTRIES, INC. (JP) 2000-02-23 EP disclosed