SCHEMBL5207595

SCHEMBL5207595

CCCCCCCC/C=C/c1[c]cccc1Cl

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 1/20 0.34
SOAT2 O75908 1/20 0.34
SOAT1 P35610 1/20 0.34
TNNC1 P63316 1/20 0.34
FAAH O00519 3/20 0.33
CYSLTR2 Q9NS75 2/20 0.33
CYSLTR1 Q9Y271 2/20 0.33
TRPV1 Q8NER1 1/20 0.33
KDM4E B2RXH2 2/20 0.33
EPHX2 P34913 1/20 0.33
LMNA P02545 1/20 0.33
MGLL Q99685 1/20 0.33
MMP2 P08253 2/20 0.32
F7 P08709 1/20 0.32
MAPT P10636 1/20 0.32
F3 P13726 1/20 0.32
ALOX15 P16050 1/20 0.32
ECE1 P42892 1/20 0.32
SGMS1 Q86VZ5 1/20 0.32
SGMS2 Q8NHU3 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5207607 1.00 L3MBTL1 (0.34) L3MBTL1SOAT2SOAT1TNNC1FAAH
SCHEMBL5204914 0.89 TLR8 (0.33)
SCHEMBL5204906 0.89 TLR8 (0.33)
SCHEMBL5206898 0.82 F7 (0.43) SOAT2SOAT1TNNC1KDM4EEPHX2
SCHEMBL5206912 0.82 F7 (0.43) SOAT2SOAT1TNNC1KDM4EEPHX2
SCHEMBL5207092 0.78 EGFR (0.36) L3MBTL1TNNC1CYSLTR2CYSLTR1KDM4E
SCHEMBL5207099 0.78 EGFR (0.36) L3MBTL1TNNC1CYSLTR2CYSLTR1KDM4E
SCHEMBL5206380 0.78 LTA4H (0.37) TRPV1EPHX2MAPT
SCHEMBL5207602 0.78 CYP2D6 (0.37) SOAT2SOAT1FAAHTRPV1KDM4E
SCHEMBL5206374 0.78 LTA4H (0.37) TRPV1EPHX2MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0980867-B1 KETONE DERIVATIVES AND MEDICINAL USE THEREOF TORAY INDUSTRIES (JP) 2007-08-08 EP disclosed
US-6100292-A Ketone derivatives and their medical applications TORAY INDUSTRIES, INC. (JP) 2000-08-08 US disclosed
EP-0980867-A1 KETONE DERIVATIVES AND MEDICINAL USE THEREOF TORAY INDUSTRIES, INC. (JP) 2000-02-23 EP disclosed