SCHEMBL5204907

SCHEMBL5204907

C#Cc1ccc(N(C(=O)c2nccnc2C(N)=O)c2ccc(NCCO[Si](C)(C)C(C)(C)C)cc2)cc1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4881556 0.82 MAPT (0.42)
SCHEMBL15862439 0.79 CETP (0.35)
SCHEMBL4882264 0.75 MAPT (0.39)
SCHEMBL4882033 0.72 MLYCD (0.42)
SCHEMBL4880731 0.72 MAPT (0.36)
SCHEMBL4881627 0.70 MAPT (0.35)
SCHEMBL4884124 0.69 DGAT1 (0.31)
SCHEMBL4886038 0.67 KMT2A (0.40)
SCHEMBL15739737 0.67 CETP (0.44)
SCHEMBL4877161 0.67 CHEK1 (0.31)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1819701-A1 CYCLIC IMINOCARBAMATES AND USE THEREOF Bayer HealthCare AG (DE) 2007-08-22 EP disclosed
WO-2006058630-A1 CYCLIC IMINOCARBAMATES AND USE THEREOF BAYER HEALTHCARE AG (DE) 2006-06-08 WO disclosed