SCHEMBL5205362

SCHEMBL5205362

CC(C)(C)CC(C)(C)c1ccc2c(c1)C(c1ccccc1)C(=O)O2

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GAA P10253 2/20 0.59
ALDH1A1 P00352 4/20 0.37
CYP19A1 P11511 1/20 0.36
HPGD P15428 2/20 0.33
SHBG P04278 1/20 0.33
HSD17B10 Q99714 1/20 0.33
MAPT P10636 2/20 0.32
SMN1; SMN2 Q16637 2/20 0.31
LMNA P02545 2/20 0.31
NPC1 O15118 1/20 0.31
MAPK1 P28482 1/20 0.31
CASP3 P42574 1/20 0.31
RAB9A P51151 1/20 0.31
ATM Q13315 1/20 0.31
SENP8 Q96LD8 1/20 0.31
SENP7 Q9BQF6 1/20 0.31
SENP6 Q9GZR1 1/20 0.31
CYP2D6 P10635 3/20 0.31
CYP1A2 P05177 2/20 0.31
CYP3A4 P08684 2/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2612456 0.85 GAA (0.67) GAAALDH1A1CYP19A1HPGDHSD17B10
SCHEMBL4689639 0.85 GAA (0.67) GAAALDH1A1CYP19A1HPGDHSD17B10
SCHEMBL26459783 0.84 CYP3A4 (0.44) GAAALDH1A1HPGDMAPTSMN1; SMN2
SCHEMBL2612468 0.84 GAA (0.65) GAAALDH1A1CYP19A1HPGDHSD17B10
SCHEMBL17172384 0.83 GAA (0.41) GAAALDH1A1HPGDSHBGMAPT
SCHEMBL2612462 0.83 GAA (0.63) GAAALDH1A1CYP19A1HPGDHSD17B10
SCHEMBL13256708 0.83 GAA (0.63) GAAALDH1A1CYP19A1HPGDHSD17B10
SCHEMBL824482 0.83 GAA (0.63) GAAALDH1A1CYP19A1HPGDHSD17B10
SCHEMBL14556835 0.82 CYP3A4 (0.41) GAAALDH1A1HPGDSHBGHSD17B10
SCHEMBL22068545 0.80 MAPT (0.40) GAAALDH1A1HPGDSHBGMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8246880-B2 Method of producing cellulose ester film, cellulose ester film, polarizing plate and liquid crystal display KONICA MINOLTA OPTO, INC. (JP) 2012-08-21 US disclosed
US-8246880-B2 Method of producing cellulose ester film, cellulose ester film, polarizing plate and liquid crystal display KONICA MINOLTA OPTO, INC. (JP) 2012-08-21 US disclosed
US-20100151156-A1 METHOD OF PRODUCING CELLULOSE ESTER FILM, CELLULOSE ESTER FILM, POLARIZING PLATE AND LIQUID CRYSTAL DISPLAY KONICA MINOLTA OPTO, INC. (JP) 2010-06-17 US disclosed
US-20100151156-A1 METHOD OF PRODUCING CELLULOSE ESTER FILM, CELLULOSE ESTER FILM, POLARIZING PLATE AND LIQUID CRYSTAL DISPLAY KONICA MINOLTA OPTO, INC. (JP) 2010-06-17 US disclosed
US-7176252-B2 Solid melt blended phosphite composites DOVER CHEMICAL CORPORATION (US) 2007-02-13 US disclosed
US-20040164279-A1 Solid melt blended phosphite composites WELLS FARGO BANK, NATIONAL ASSOCIATION 2004-08-26 US disclosed
EP-0545861-B1 Diphenylacetic acid derivatives as stabilisers for organic material CIBA GEIGY AG (CH) 1995-12-27 EP disclosed
US-5260430-A Stabilizers for organic materials against oxidative, thermal and light degradation CIBA-GEIGY CORPORATION (US) 1993-11-09 US disclosed
EP-0545861-A2 Diphenylacetic acid derivatives as stabilisers for organic material CIBA-GEIGY AG (CH) 1993-06-09 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040164279-A1 Solid melt blended phosphite composites PHOSPHO1, MTAP, INPPL1 GAA 2474/4885ALDH1A1 2924/4885CYP19A1 3321/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.