Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 3/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 4/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | ESR1 | P03372 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | APAF1 | O14727 | 2/20 | 0.36 |
| ▸ | USP2 | O75604 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | ERBB2 | P04626 | 2/20 | 0.36 |
| ▸ | TP53 | P04637 | 2/20 | 0.36 |
| ▸ | FYN | P06241 | 2/20 | 0.36 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.36 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.36 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.36 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.36 |
| ▸ | HSPD1 | P10809 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26459796 | 0.93 | CYP3A4 (0.39) | CYP3A4SMN1; SMN2GAAALDH1A1HPGD | |
| SCHEMBL5205362 | 0.84 | GAA (0.59) | CYP3A4SMN1; SMN2GAAALDH1A1HPGD | |
| SCHEMBL22068545 | 0.80 | MAPT (0.40) | CYP3A4SMN1; SMN2GAAALDH1A1HPGD | |
| SCHEMBL17172384 | 0.78 | GAA (0.41) | CYP3A4GAAALDH1A1HPGDHIF1A | |
| SCHEMBL23071652 | 0.78 | GAA (0.34) | CYP3A4SMN1; SMN2GAAALDH1A1HPGD | |
| SCHEMBL18590074 | 0.78 | GAA (0.34) | CYP3A4SMN1; SMN2GAAALDH1A1HPGD | |
| SCHEMBL22202050 | 0.77 | GAA (0.34) | CYP3A4SMN1; SMN2GAAALDH1A1HPGD | |
| SCHEMBL22068557 | 0.77 | GAA (0.34) | CYP3A4SMN1; SMN2GAAALDH1A1HPGD | |
| SCHEMBL466198 | 0.77 | GAA (0.34) | CYP3A4SMN1; SMN2GAAALDH1A1HPGD | |
| SCHEMBL14556835 | 0.77 | CYP3A4 (0.41) | CYP3A4SMN1; SMN2GAAALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230127329-A1 | LACTONE COMPOUND | FUJIFILM CORPORATION (JP) | 2023-04-27 | — | — | US | disclosed |
| US-20230127329-A1 | LACTONE COMPOUND | FUJIFILM CORPORATION (JP) | 2023-04-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230127329-A1 | LACTONE COMPOUND | LANCL1, GPX1, LOXL1 | CYP3A4 171/4885SMN1; SMN2 4311/4885GAA 503/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.