SCHEMBL824482

SCHEMBL824482

CC(C)(c1ccccc1)c1ccc2c(c1)C(c1ccccc1)C(=O)O2

nearest known ligand 0.63

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
GAA P10253 2/20 0.63
ALDH1A1 P00352 5/20 0.39
CYP19A1 P11511 1/20 0.38
ESR1 P03372 2/20 0.37
ESR2 Q92731 2/20 0.37
CYP3A4 P08684 2/20 0.37
HPGD P15428 2/20 0.35
HSD17B10 Q99714 1/20 0.35
CYP2C9 P11712 1/20 0.34
NR3C2 P08235 2/20 0.34
MAPT P10636 2/20 0.34
MEN1 O00255 2/20 0.33
KMT2A Q03164 2/20 0.33
CNR1 P21554 1/20 0.33
CNR2 P34972 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2612468 0.99 GAA (0.65) GAAALDH1A1CYP19A1ESR1ESR2
SCHEMBL2612456 0.97 GAA (0.67) GAAALDH1A1CYP19A1ESR1ESR2
SCHEMBL2612462 0.89 GAA (0.63) GAAALDH1A1CYP19A1ESR1ESR2
SCHEMBL4689639 0.89 GAA (0.67) GAAALDH1A1CYP19A1CYP3A4HPGD
SCHEMBL11987177 0.87 GAA (0.59) GAAALDH1A1CYP19A1HPGDHSD17B10
SCHEMBL13256708 0.86 GAA (0.63) GAAALDH1A1CYP19A1ESR1ESR2
SCHEMBL5205362 0.83 GAA (0.59) GAAALDH1A1CYP19A1CYP3A4HPGD
SCHEMBL824537 0.78 GAA (0.44) GAAALDH1A1ESR1ESR2CYP3A4
SCHEMBL2612466 0.78 GAA (0.53) GAAALDH1A1CYP19A1HPGDHSD17B10
SCHEMBL2612450 0.76 GAA (0.50) GAAALDH1A1CYP19A1CYP3A4HSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 34 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6224791-B1 PHENYLBENZOFURAN-2-ONE WITH PHOSPHITE DOVER CHEMICAL CORPORATION 2001-05-01 US claimed
WO-1999003915-A1 LACTONE/PHOSPHITE BLENDS DOVER CHEMICAL CORPORATION (US) 1999-01-28 WO claimed
US-20140234640-A1 GAS BARRIER FILM, MANUFACTURING METHOD THEREOF, AND SUBSTRATE FOR ELECTRONIC ELEMENT USING THE SAME Konica Minolta, Inc. (JP) 2014-08-21 US disclosed
US-20140234640-A1 GAS BARRIER FILM, MANUFACTURING METHOD THEREOF, AND SUBSTRATE FOR ELECTRONIC ELEMENT USING THE SAME Konica Minolta, Inc. (JP) 2014-08-21 US disclosed
US-8246880-B2 Method of producing cellulose ester film, cellulose ester film, polarizing plate and liquid crystal display KONICA MINOLTA OPTO, INC. (JP) 2012-08-21 US disclosed
US-8246880-B2 Method of producing cellulose ester film, cellulose ester film, polarizing plate and liquid crystal display KONICA MINOLTA OPTO, INC. (JP) 2012-08-21 US disclosed
US-8142864-B2 Cellulose ester pellets, cellulose ester film, manufacturing method of cellulose ester film, polarizing plate, and liquid crystal display KONICA MINOLTA OPTO, INC. (JP) 2012-03-27 US disclosed
US-8142864-B2 Cellulose ester pellets, cellulose ester film, manufacturing method of cellulose ester film, polarizing plate, and liquid crystal display KONICA MINOLTA OPTO, INC. (JP) 2012-03-27 US disclosed
US-20100164141-A1 Cellulose Ester Film, Its Manufacturing Method, Polarizing Plate, and Liquid Crystal Display KONICA MINOLTA OPTO, INC. (JP) 2010-07-01 US disclosed
US-20100164141-A1 Cellulose Ester Film, Its Manufacturing Method, Polarizing Plate, and Liquid Crystal Display KONICA MINOLTA OPTO, INC. (JP) 2010-07-01 US disclosed
US-20100151156-A1 METHOD OF PRODUCING CELLULOSE ESTER FILM, CELLULOSE ESTER FILM, POLARIZING PLATE AND LIQUID CRYSTAL DISPLAY KONICA MINOLTA OPTO, INC. (JP) 2010-06-17 US disclosed
US-20070128380-A1 Cellulose Ester Film, Its Manufacturing Method, Polarizing Plate, and Liquid Crystal Display KONICA MINOLTA OPTO, INC. (JP) 2007-06-07 US disclosed
CN-1890254-A Process for manufacture of pentaerythritol diphosphites DOVER CHEMICAL CORP (US) 2007-01-03 CN disclosed
WO-2005113665-A2 PHENOL-FREE PHOSPHITES DOVER CHEMICAL CORPORATION (US) 2005-12-01 WO disclosed
US-20050131244-A1 PROCESS FOR MANUFACTURE OF PENTAERYTHRITOL DIPHOSPHITES DOVER CHEMICAL CORPORATION (US) 2005-06-16 US disclosed
US-20040180999-A1 PHENOL-FREE PHOSPHITES DOVER CHEMICAL CORPORATION (US) 2004-09-16 US disclosed
US-6770693-B2 COMPRISING BIS-(2,4-DICUMYLPHENYL) PENTAERYTHRITOL DIPHOSPHITE AND HINDERED PHENOL ANTIOXIDANTS USEFUL AS STABILIZERS AGAINST THERMOOXIDATIVE DEGRADATION OF POLYMERS DURING MELT PROCESSING DOVE CHEMICAL CORPORATION 2004-08-03 US disclosed
US-20020040081-A1 Blends of phosphites and antioxidants DOVER CHEMICAL 2002-04-04 US disclosed
US-6224791-B1 PHENYLBENZOFURAN-2-ONE WITH PHOSPHITE DOVER CHEMICAL CORPORATION 2001-05-01 US disclosed
WO-1999003915-A1 LACTONE/PHOSPHITE BLENDS DOVER CHEMICAL CORPORATION (US) 1999-01-28 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050131244-A1 PROCESS FOR MANUFACTURE OF PENTAERYTHRITOL DIPHOSPHITES GNPAT, DCTPP1, DERA GAA 2344/4885ALDH1A1 619/4885CYP19A1 1302/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.