Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSPO | P30536 | 1/20 | 0.41 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | TAOK1 | Q7L7X3 | 1/20 | 0.38 |
| ▸ | TAOK3 | Q9H2K8 | 1/20 | 0.38 |
| ▸ | HTR5A | P47898 | 1/20 | 0.38 |
| ▸ | DGAT2 | Q96PD7 | 1/20 | 0.38 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL5204683 | 0.96 | DGAT2 (0.41) | TSPOLTB4R2ALDH1A1MEN1KMT2A | |
| Trifluoroacetic Acid SCHEMBL5204867 | 0.94 | ALDH1A1 (0.42) | TSPOLTB4R2ALDH1A1MEN1KMT2A | |
| Trifluoroacetic Acid SCHEMBL5205650 | 0.94 | TAOK1 (0.38) | ALDH1A1KDM4EHTTTDP1TAOK1 | |
| Trifluoroacetic Acid SCHEMBL5202054 | 0.93 | TSPO (0.39) | TSPOEPHX2 | |
| Trifluoroacetic Acid SCHEMBL5202498 | 0.93 | EPHX2 (0.38) | TSPOALDH1A1KDM4EHTTTDP1 | |
| Trifluoroacetic Acid SCHEMBL5205999 | 0.92 | ALDH1A1 (0.46) | TSPOALDH1A1MEN1KMT2A | |
| Trifluoroacetic Acid SCHEMBL5208213 | 0.92 | TAOK1 (0.37) | TSPOALDH1A1KDM4EHTTTDP1 | |
| Trifluoroacetic Acid SCHEMBL5208369 | 0.91 | BACE1 (0.45) | LTB4R2TAOK1TAOK3EPHX2 | |
| Trifluoroacetic Acid SCHEMBL5204269 | 0.91 | KMT2A (0.43) | TSPOALDH1A1MEN1KMT2AKDM4E | |
| Trifluoroacetic Acid SCHEMBL5205759 | 0.90 | TAOK1 (0.36) | TSPOALDH1A1MEN1KMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7160887-B1 | Aromatic amine derivatives, their production and use | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2007-01-09 | — | — | US | disclosed |
| EP-1123918-B1 | AROMATIC AMINE DERIVATIVES, PROCESS FOR THE PREPARATION THEREOF AND AGENTS CONTAINING THE SAME | TAKEDA PHARMACEUTICAL (JP) | 2005-03-09 | — | — | EP | disclosed |
| EP-1123918-A1 | AROMATIC AMINE DERIVATIVES, PROCESS FOR THE PREPARATION THEREOF AND AGENTS CONTAINING THE SAME | Takeda Chemical Industries, Ltd. (JP) | 2001-08-16 | — | — | EP | disclosed |