Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCL1 | Q07820 | 1/20 | 0.39 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.34 |
| ▸ | DHODH | Q02127 | 1/20 | 0.34 |
| ▸ | CCR5 | P51681 | 4/20 | 0.34 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.34 |
| ▸ | BRD4 | O60885 | 1/20 | 0.34 |
| ▸ | BRD2 | P25440 | 1/20 | 0.34 |
| ▸ | BRD3 | Q15059 | 1/20 | 0.34 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.33 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.33 |
| ▸ | SRD5A1 | P18405 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27520896 | 0.85 | KDM4E (0.39) | KDM4EHDAC4CCR5ALDH1A1TP53 | |
| SCHEMBL5206950 | 0.83 | SRD5A1 (0.38) | NOTUMKDM4ECCR5SRD5A1ALDH1A1 | |
| SCHEMBL5240544 | 0.80 | MYC (0.39) | MCL1KDM4ESRD5A1ALDH1A1HPGD | |
| SCHEMBL3498780 | 0.79 | MAPT (0.34) | MCL1KDM4ECYP11B1CYP11B2 | |
| Hydrochloric Acid SCHEMBL5204621 | 0.78 | MYC (0.38) | MCL1SRD5A1ALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL3499816 | 0.74 | CCR5 (0.53) | MCL1CCR5ALDH1A1NPC1RAB9A | |
| SCHEMBL6350453 | 0.73 | MAPT (0.41) | MCL1TP53RAB9ASMN1; SMN2CYP11B1 | |
| SCHEMBL5549419 | 0.72 | TNKS (0.41) | MCL1KDM4ESRD5A1ALDH1A1TSHR | |
| SCHEMBL5549424 | 0.72 | TNKS (0.41) | MCL1KDM4ESRD5A1ALDH1A1TSHR | |
| SCHEMBL3499129 | 0.72 | MCL1 (0.40) | MCL1DHODHCCR5AKR1C2AKR1C1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1040103-B1 | ANILIDE DERIVATIVE, PRODUCTION AND USE THEREOF | TAKEDA PHARMACEUTICAL (JP) | 2007-03-14 | — | — | EP | disclosed |
| US-6413947-B1 | Anilide derivative, production and use thereof | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2002-07-02 | — | — | US | disclosed |