Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNA2 | P20248 | 1/20 | 0.53 |
| ▸ | CDK2 | P24941 | 1/20 | 0.53 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.53 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.46 |
| ▸ | WEE1 | P30291 | 2/20 | 0.44 |
| ▸ | PKMYT1 | Q99640 | 2/20 | 0.44 |
| ▸ | NOS1 | P29475 | 4/20 | 0.41 |
| ▸ | RIPK2 | O43353 | 2/20 | 0.40 |
| ▸ | IDO1 | P14902 | 1/20 | 0.39 |
| ▸ | TDO2 | P48775 | 1/20 | 0.39 |
| ▸ | PIM1 | P11309 | 1/20 | 0.38 |
| ▸ | GRK2 | P25098 | 1/20 | 0.38 |
| ▸ | ROCK1 | Q13464 | 2/20 | 0.37 |
| ▸ | AXL | P30530 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24112905 | 0.81 | WEE1 (0.52) | CCNA2CDK2CCNA1WEE1PKMYT1 | |
| SCHEMBL12321248 | 0.74 | NOS1 (0.56) | CCNA2CDK2CCNA1NOS1IDO1 | |
| SCHEMBL12439133 | 0.74 | IDO1 (0.46) | CCNA2CDK2CCNA1NOS1IDO1 | |
| SCHEMBL25288291 | 0.72 | CCNA2 (0.53) | CCNA2CDK2CCNA1PDPK1WEE1 | |
| SCHEMBL26403639 | 0.71 | CCNA2 (0.51) | CCNA2CDK2CCNA1PDPK1WEE1 | |
| SCHEMBL25776367 | 0.71 | CCNA2 (0.48) | CCNA2CDK2CCNA1WEE1PKMYT1 | |
| SCHEMBL7572936 | 0.71 | IDO1 (0.43) | CCNA2CDK2CCNA1NOS1IDO1 | |
| SCHEMBL18038216 | 0.71 | NOS1 (0.50) | CCNA2CDK2CCNA1NOS1IDO1 | |
| SCHEMBL5929682 | 0.71 | IDO1 (0.52) | CCNA2CDK2CCNA1PDPK1NOS1 | |
| SCHEMBL16178599 | 0.71 | TRPA1 (0.47) | CCNA2CDK2CCNA1NOS1IDO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117327643-A | Method for obtaining definitive endoderm cells from human pluripotent stem cells by using YAP inhibitor | 武汉大学 | 2024-01-02 | — | — | CN | disclosed |
| CN-115414283-B | Pericarpium citri reticulatae essential oil massage oil and preparation method and application thereof | 广东新会宝皮宝陈皮文化有限公司 | 2023-11-28 | — | — | CN | disclosed |
| CN-113813280-B | Sugar ring modified compound, preparation method and application thereof in preparation of products with anti-fatigue function | 中国人民解放军军事科学院军事医学研究院 | 2023-07-07 | — | — | CN | disclosed |
| CN-116284180-A | Use of golden-silk-flos chrysanthemi-flavonoid glycoside in preparing medicament for treating hyperlipidemia and fatty liver | 江苏灵源沂岸科技股份有限公司 | 2023-06-23 | — | — | CN | disclosed |
| EP-1294722-B1 | METHODS OF SYNTHESIS FOR 9-SUBSTITUTED HYPOXANTHINE DERIVATIVES | MERCK EPROVA AG (CH) | 2007-08-01 | — | — | EP | disclosed |