Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNA2 | P20248 | 1/20 | 0.48 |
| ▸ | CDK2 | P24941 | 1/20 | 0.48 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.48 |
| ▸ | PIM1 | P11309 | 1/20 | 0.40 |
| ▸ | SYK | P43405 | 6/20 | 0.39 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.39 |
| ▸ | BTK | Q06187 | 2/20 | 0.39 |
| ▸ | PLK4 | O00444 | 1/20 | 0.39 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.39 |
| ▸ | AURKA | O14965 | 1/20 | 0.39 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.39 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.39 |
| ▸ | CSF1R | P07333 | 1/20 | 0.39 |
| ▸ | RET | P07949 | 1/20 | 0.39 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.39 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.39 |
| ▸ | LTK | P29376 | 1/20 | 0.39 |
| ▸ | KDR | P35968 | 1/20 | 0.39 |
| ▸ | MAP2K2 | P36507 | 1/20 | 0.39 |
| ▸ | FLT3 | P36888 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25288291 | 0.78 | CCNA2 (0.53) | CCNA2CDK2CCNA1PIM1BTK | |
| SCHEMBL26403639 | 0.76 | CCNA2 (0.51) | CCNA2CDK2CCNA1PIM1BTK | |
| SCHEMBL4144293 | 0.76 | CCNA2 (0.48) | CCNA2CDK2CCNA1PIM1SYK | |
| SCHEMBL25776372 | 0.76 | JAK3 (0.50) | CDK2SYKBTKPLK4CHEK1 | |
| SCHEMBL5401834 | 0.76 | P4HB (0.48) | CCNA2CDK2CCNA1ROCK2FGFR1 | |
| SCHEMBL25278751 | 0.74 | CCNA2 (0.44) | CCNA2CDK2CCNA1PIM1SYK | |
| SCHEMBL31140728 | 0.74 | CCNA2 (0.44) | CCNA2CDK2CCNA1PIM1SYK | |
| SCHEMBL2882576 | 0.74 | IRAK4 (0.44) | PTK2 | |
| SCHEMBL16746127 | 0.74 | TRPA1 (0.42) | CDK2CCNA1ROCK2FLT3NOS1 | |
| SCHEMBL12110234 | 0.74 | METAP2 (0.46) | CDK2CCNA1ROCK2FLT3NOS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023116779-A1 | DIALKYNE COMPOUND AND USE THEREOF | 上海艾力斯医药科技股份有限公司 | 2023-06-29 | — | — | WO | disclosed |