Trifluoroacetic Acid

Trifluoroacetic Acid

SCHEMBL5205822

CC1CCc2sc(C(N)=O)nc2C1.NCc1cccc(C(=O)N(CC(=O)O)c2ccccc2)c1.O=C(O)C(F)(F)F

nearest known ligand 0.34

Full drug profile on Sugi Atlas →

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
F2 P00734 4/20 0.34
TPSAB1 Q15661 4/20 0.33
HRH2 P25021 1/20 0.32
HRH1 P35367 1/20 0.32
HRH4 Q9H3N8 1/20 0.32
HRH3 Q9Y5N1 1/20 0.32
ACHE P22303 1/20 0.31
LMNA P02545 1/20 0.31
OPRM1 P35372 4/20 0.31
OPRD1 P41143 4/20 0.31
KMT2A Q03164 2/20 0.31
MEN1 O00255 1/20 0.31
PKM P14618 1/20 0.31
KLKB1 P03952 1/20 0.31
F10 P00742 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Trifluoroacetic Acid SCHEMBL6993355 0.96 OPRM1 (0.33) F2TPSAB1HRH2HRH1HRH4
Trifluoroacetic Acid SCHEMBL5207971 0.94 HRH2 (0.37) F2TPSAB1HRH2HRH1HRH4
Trifluoroacetic Acid SCHEMBL5206361 0.91 HRH2 (0.34) F2TPSAB1HRH2HRH1HRH4
Trifluoroacetic Acid SCHEMBL6999298 0.90 HRH2 (0.37) TPSAB1HRH2HRH1HRH4HRH3
Trifluoroacetic Acid SCHEMBL6996192 0.87 HRH2 (0.34) TPSAB1HRH2HRH1HRH4HRH3
SCHEMBL5210132 0.83 F2 (0.39) F2LMNAKMT2AMEN1PKM
Trifluoroacetic Acid SCHEMBL5209729 0.83 F2 (0.34) F2TPSAB1OPRM1OPRD1KMT2A
Trifluoroacetic Acid SCHEMBL5208680 0.80 KDM4E (0.36) LMNAOPRM1OPRD1
Trifluoroacetic Acid SCHEMBL5211180 0.80 NPC1 (0.39) F2LMNA
Trifluoroacetic Acid SCHEMBL5205875 0.79 RAD52 (0.40) F2KMT2AMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1343561-B1 SERINE PROTEASE INHIBITORS TULARIK LTD (GB) 2007-02-28 EP disclosed