Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAD52 | P43351 | 4/20 | 0.40 |
| ▸ | TP53 | P04637 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | ADORA2A | P29274 | 4/20 | 0.36 |
| ▸ | ADORA2B | P29275 | 4/20 | 0.36 |
| ▸ | ADORA1 | P30542 | 4/20 | 0.36 |
| ▸ | F2 | P00734 | 2/20 | 0.36 |
| ▸ | REN | P00797 | 2/20 | 0.35 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL5207641 | 0.95 | RAD52 (0.42) | RAD52TP53MAPTADORA2AADORA2B | |
| Trifluoroacetic Acid SCHEMBL6995379 | 0.95 | TP53 (0.39) | RAD52TP53MAPTADORA2AADORA2B | |
| Trifluoroacetic Acid SCHEMBL5211772 | 0.91 | RAD52 (0.41) | RAD52TP53MAPTF2MEN1 | |
| Trifluoroacetic Acid SCHEMBL6999399 | 0.91 | RAD52 (0.41) | RAD52TP53MAPTADORA2AADORA2B | |
| Trifluoroacetic Acid SCHEMBL5208806 | 0.85 | MAPT (0.37) | TP53MAPTF2MEN1KMT2A | |
| Trifluoroacetic Acid SCHEMBL5207907 | 0.84 | MAPT (0.43) | TP53MAPTF2MEN1KMT2A | |
| Trifluoroacetic Acid SCHEMBL5204087 | 0.83 | LMNA (0.37) | TP53MAPTF2MEN1KMT2A | |
| Trifluoroacetic Acid SCHEMBL5211180 | 0.83 | NPC1 (0.39) | TP53MAPTF2 | |
| Trifluoroacetic Acid SCHEMBL5210737 | 0.82 | F2 (0.38) | MAPTF2MEN1KMT2A | |
| Trifluoroacetic Acid SCHEMBL5209105 | 0.81 | TP53 (0.38) | TP53MAPTF2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1343561-B1 | SERINE PROTEASE INHIBITORS | TULARIK LTD (GB) | 2007-02-28 | — | — | EP | disclosed |