Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAD52 | P43351 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 4/20 | 0.38 |
| ▸ | TP53 | P04637 | 4/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | CHRM4 | P08173 | 3/20 | 0.35 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.35 |
| ▸ | ADORA2B | P29275 | 2/20 | 0.35 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.35 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.35 |
| ▸ | UBA2 | Q9UBT2 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | F2 | P00734 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL6999399 | 0.95 | RAD52 (0.41) | RAD52MAPTTP53POLBLMNA | |
| Trifluoroacetic Acid SCHEMBL5205875 | 0.95 | RAD52 (0.40) | RAD52MAPTTP53ADORA2AADORA2B | |
| Trifluoroacetic Acid SCHEMBL6995379 | 0.91 | TP53 (0.39) | RAD52MAPTTP53ADORA2AADORA2B | |
| Trifluoroacetic Acid SCHEMBL5211772 | 0.89 | RAD52 (0.41) | RAD52MAPTTP53POLBLMNA | |
| Trifluoroacetic Acid SCHEMBL5208806 | 0.85 | MAPT (0.37) | MAPTTP53POLBLMNAGAA | |
| Trifluoroacetic Acid SCHEMBL5210737 | 0.82 | F2 (0.38) | MAPTF2 | |
| Trifluoroacetic Acid SCHEMBL5207907 | 0.81 | MAPT (0.43) | MAPTTP53POLBLMNAF2 | |
| Trifluoroacetic Acid SCHEMBL7432339 | 0.81 | LMNA (0.37) | MAPTTP53POLBLMNAGAA | |
| Trifluoroacetic Acid SCHEMBL5204087 | 0.81 | LMNA (0.37) | MAPTTP53LMNAF2 | |
| Trifluoroacetic Acid SCHEMBL5211180 | 0.80 | NPC1 (0.39) | MAPTTP53LMNAGAAHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1343561-B1 | SERINE PROTEASE INHIBITORS | TULARIK LTD (GB) | 2007-02-28 | — | — | EP | disclosed |
| EP-1343561-A1 | SERINE PROTEASE INHIBITORS | Tularik Limited (GB) | 2003-09-17 | — | — | EP | disclosed |
| WO-2002047762-A1 | SERINE PROTEASE INHIBITORS | TULARIK LIMITED (GB) | 2002-06-20 | — | — | WO | disclosed |