Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAD52 | P43351 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 5/20 | 0.38 |
| ▸ | TP53 | P04637 | 5/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | CHRM4 | P08173 | 3/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.35 |
| ▸ | UBA2 | Q9UBT2 | 1/20 | 0.35 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.35 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.35 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL5207641 | 0.95 | RAD52 (0.42) | RAD52MAPTTP53POLBLMNA | |
| Trifluoroacetic Acid SCHEMBL6995379 | 0.95 | TP53 (0.39) | RAD52MAPTTP53NPC1RAB9A | |
| Trifluoroacetic Acid SCHEMBL5205875 | 0.91 | RAD52 (0.40) | RAD52MAPTTP53ADORA2AADORA2B | |
| Trifluoroacetic Acid SCHEMBL7432339 | 0.85 | LMNA (0.37) | MAPTTP53POLBLMNAGAA | |
| Trifluoroacetic Acid SCHEMBL5211772 | 0.84 | RAD52 (0.41) | RAD52MAPTTP53POLBLMNA | |
| Trifluoroacetic Acid SCHEMBL5208806 | 0.81 | MAPT (0.37) | MAPTTP53POLBLMNAGAA | |
| Trifluoroacetic Acid SCHEMBL5210737 | 0.78 | F2 (0.38) | MAPT | |
| Trifluoroacetic Acid SCHEMBL6993355 | 0.77 | OPRM1 (0.33) | LMNA | |
| Trifluoroacetic Acid SCHEMBL5207907 | 0.77 | MAPT (0.43) | MAPTTP53POLBLMNANPC1 | |
| Trifluoroacetic Acid SCHEMBL5204087 | 0.76 | LMNA (0.37) | MAPTTP53LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1343561-A1 | SERINE PROTEASE INHIBITORS | Tularik Limited (GB) | 2003-09-17 | — | — | EP | disclosed |
| WO-2002047762-A1 | SERINE PROTEASE INHIBITORS | TULARIK LIMITED (GB) | 2002-06-20 | — | — | WO | disclosed |