Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 1/20 | 0.50 |
| ▸ | PPARG | P37231 | 13/20 | 0.49 |
| ▸ | PPARA | Q07869 | 12/20 | 0.49 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | TP53 | P04637 | 3/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5210317 | 0.98 | FFAR1 (0.52) | FFAR1PPARGPPARAMAPTTP53 | |
| SCHEMBL5210569 | 0.93 | FFAR1 (0.53) | FFAR1PPARGPPARAMAPTTP53 | |
| SCHEMBL5205909 | 0.93 | PPARA (0.49) | FFAR1PPARGPPARAMAPTTP53 | |
| SCHEMBL5211136 | 0.91 | PPARG (0.56) | PPARGPPARA | |
| SCHEMBL5209719 | 0.91 | PPARG (0.47) | FFAR1PPARGPPARAMAPTTP53 | |
| SCHEMBL2524236 | 0.89 | FFAR1 (0.52) | FFAR1PPARGPPARAMAPTTP53 | |
| SCHEMBL2524237 | 0.89 | FFAR1 (0.52) | FFAR1PPARGPPARAMAPTTP53 | |
| SCHEMBL5210493 | 0.88 | PPARA (0.50) | FFAR1PPARGPPARAMAPTTP53 | |
| SCHEMBL2523256 | 0.87 | FFAR1 (0.54) | FFAR1PPARGPPARAMAPT | |
| SCHEMBL2523261 | 0.87 | FFAR1 (0.54) | FFAR1PPARGPPARAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1448523-B1 | HETEROCYCLIC COMPOUNDS AND METHODS OF USE | NOVARTIS AG (CH) | 2007-08-22 | — | — | EP | claimed |