Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 10/20 | 0.49 |
| ▸ | PPARG | P37231 | 9/20 | 0.49 |
| ▸ | MMP1 | P03956 | 5/20 | 0.44 |
| ▸ | TP53 | P04637 | 2/20 | 0.44 |
| ▸ | ADAM17 | P78536 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5210493 | 0.95 | PPARA (0.50) | PPARAPPARGTP53POLBMAPT | |
| SCHEMBL5205913 | 0.93 | FFAR1 (0.50) | PPARAPPARGTP53MAPTFFAR1 | |
| SCHEMBL5210317 | 0.93 | FFAR1 (0.52) | PPARAPPARGMMP1TP53ADAM17 | |
| SCHEMBL5209719 | 0.91 | PPARG (0.47) | PPARAPPARGTP53MAPTFFAR1 | |
| SCHEMBL2518121 | 0.90 | PPARA (0.51) | PPARAPPARGMMP1TP53ADAM17 | |
| SCHEMBL2518126 | 0.90 | PPARA (0.51) | PPARAPPARGMMP1TP53ADAM17 | |
| SCHEMBL5210445 | 0.88 | PPARA (0.48) | PPARAPPARGMMP1ADAM17FFAR1 | |
| SCHEMBL5210569 | 0.88 | FFAR1 (0.53) | PPARAPPARGTP53MAPTFFAR1 | |
| SCHEMBL5211136 | 0.87 | PPARG (0.56) | PPARAPPARG | |
| SCHEMBL5207399 | 0.86 | PPARA (0.42) | PPARAPPARGTP53POLBMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1448523-B1 | HETEROCYCLIC COMPOUNDS AND METHODS OF USE | NOVARTIS AG (CH) | 2007-08-22 | — | — | EP | claimed |