Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 8/20 | 0.47 |
| ▸ | PPARA | Q07869 | 7/20 | 0.47 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.45 |
| ▸ | PPARD | Q03181 | 3/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | SPHK2 | Q9NRA0 | 2/20 | 0.42 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.42 |
| ▸ | KCNQ1 | P51787 | 1/20 | 0.42 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5211867 | 0.95 | PPARG (0.48) | PPARGPPARAPTPN1PPARDCYP2C9 | |
| SCHEMBL5210445 | 0.93 | PPARA (0.48) | PPARGPPARACYP2C9KCNH2FFAR1 | |
| SCHEMBL5208392 | 0.93 | PPARA (0.55) | PPARGPPARAPTPN1 | |
| SCHEMBL5205909 | 0.91 | PPARA (0.49) | PPARGPPARAMAPTFFAR1TP53 | |
| SCHEMBL5205913 | 0.91 | FFAR1 (0.50) | PPARGPPARAMAPTFFAR1TP53 | |
| SCHEMBL5210317 | 0.90 | FFAR1 (0.52) | PPARGPPARAMAPTFFAR1TP53 | |
| SCHEMBL2518483 | 0.90 | PPARG (0.50) | PPARGPPARAPTPN1PPARDCYP2C9 | |
| SCHEMBL2518481 | 0.90 | PPARG (0.50) | PPARGPPARAPTPN1PPARDCYP2C9 | |
| SCHEMBL5210899 | 0.88 | PPARA (0.49) | PPARGPPARACYP2C9KCNH2MAPT | |
| SCHEMBL5206559 | 0.87 | MAPT (0.46) | PPARGPPARAPPARDMAPTKCNQ1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1448523-B1 | HETEROCYCLIC COMPOUNDS AND METHODS OF USE | NOVARTIS AG (CH) | 2007-08-22 | — | — | EP | claimed |