Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 1/20 | 0.53 |
| ▸ | PPARG | P37231 | 13/20 | 0.52 |
| ▸ | PPARA | Q07869 | 11/20 | 0.52 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | KDR | P35968 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5210317 | 0.95 | FFAR1 (0.52) | FFAR1PPARGPPARAMAPTKDR | |
| SCHEMBL5205913 | 0.93 | FFAR1 (0.50) | FFAR1PPARGPPARAMAPTTP53 | |
| SCHEMBL5210493 | 0.92 | PPARA (0.50) | FFAR1PPARGPPARAMAPTTP53 | |
| SCHEMBL5210810 | 0.92 | PPARG (0.57) | PPARGPPARA | |
| SCHEMBL5211867 | 0.90 | PPARG (0.48) | FFAR1PPARGPPARAMAPTTP53 | |
| SCHEMBL5210899 | 0.88 | PPARA (0.49) | FFAR1PPARGPPARAMAPTTP53 | |
| SCHEMBL2521135 | 0.88 | FFAR1 (0.55) | FFAR1PPARGPPARAMAPT | |
| SCHEMBL2521132 | 0.88 | FFAR1 (0.55) | FFAR1PPARGPPARAMAPT | |
| SCHEMBL5205909 | 0.88 | PPARA (0.49) | FFAR1PPARGPPARAMAPTTP53 | |
| SCHEMBL5211136 | 0.87 | PPARG (0.56) | PPARGPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1448523-B1 | HETEROCYCLIC COMPOUNDS AND METHODS OF USE | NOVARTIS AG (CH) | 2007-08-22 | — | — | EP | claimed |