SCHEMBL5205978

SCHEMBL5205978

CC[CH]C(=O)NC(CC)C(C)C

nearest known ligand 0.38

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
TAS1R3 Q7RTX0 2/20 0.36
TAS1R1 Q7RTX1 2/20 0.36
MMP1 P03956 1/20 0.31
MMP2 P08253 1/20 0.31
MMP3 P08254 1/20 0.31
TSHR P16473 1/20 0.31
CA1 P00915 1/20 0.31
CA2 P00918 1/20 0.31
CA7 P43166 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5211819 0.86 ALDH1A1 (0.35) MMP1MMP2MMP3TSHR
SCHEMBL5203991 0.84 TAS1R3 (0.37) TAS1R3TAS1R1
SCHEMBL5211254 0.81 TAS1R3 (0.36) TAS1R3TAS1R1MMP1MMP2MMP3
SCHEMBL5209088 0.78 MMP1 (0.47) TAS1R3TAS1R1MMP1MMP2MMP3
SCHEMBL6300919 0.78
SCHEMBL4894902 0.76
SCHEMBL5211493 0.76 CA12 (0.45) TAS1R3TAS1R1MMP1MMP2CA1
SCHEMBL4896267 0.74 HTT (0.32) MMP1MMP2CA1CA2
SCHEMBL5204828 0.73 PRSS1 (0.31) TSHR
SCHEMBL8437778 0.73 ALDH1A1 (0.40) TAS1R3TAS1R1MMP1MMP2MMP3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0958292-B1 4-(3-HETEROCYCLYL-1-BENZOYL)PYRAZOLES AND THEIR USE AS HERBICIDES BASF AG (DE) 2007-01-03 EP disclosed
US-6165944-A 4-(3-heterocyclyl-1-benzoyl) pyrazoles and their use as herbicides BASF AKTIENGESELLSCHAFT (DE) 2000-12-26 US disclosed
EP-0958292-A1 4-(3-HETEROCYCLYL-1-BENZOYL)PYRAZOLES AND THEIR USE AS HERBICIDES BASF AKTIENGESELLSCHAFT (DE) 1999-11-24 EP disclosed
WO-1998031682-A1 4-(3-HETEROCYCLYL-1-BENZOYL)PYRAZOLES AND THEIR USE AS HERBICIDES BASF AKTIENGESELLSCHAFT (DE) 1998-07-23 WO disclosed