Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGES | O14684 | 1/20 | 0.45 |
| ▸ | BCHE | P06276 | 1/20 | 0.44 |
| ▸ | SLC2A1 | P11166 | 2/20 | 0.44 |
| ▸ | BACE1 | P56817 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | F10 | P00742 | 1/20 | 0.41 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.41 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.41 |
| ▸ | CTSV | O60911 | 1/20 | 0.41 |
| ▸ | CTSL | P07711 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.41 |
| ▸ | CETP | P11597 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5204827 | 0.85 | TDP1 (0.41) | PTGESMAPTMEN1KMT2APOLB | |
| SCHEMBL6176918 | 0.79 | FFAR1 (0.50) | BCHEBACE1MAPTMEN1KMT2A | |
| SCHEMBL5202945 | 0.78 | ALDH1A1 (0.48) | MAPTMEN1KMT2APTGS1PTGS2 | |
| SCHEMBL14673865 | 0.77 | MAPT (0.44) | PTGESMAPTMEN1KMT2AALOX5 | |
| SCHEMBL503298 | 0.76 | SLC2A1 (0.46) | SLC2A1MAPTMEN1KMT2AALOX5 | |
| SCHEMBL7907625 | 0.74 | MEN1 (0.54) | PTGESBACE1MAPTMEN1KMT2A | |
| SCHEMBL27490731 | 0.74 | BACE1 (0.52) | BACE1MAPTMEN1KMT2A | |
| SCHEMBL14674248 | 0.73 | LPAR1 (0.44) | — | |
| SCHEMBL646471 | 0.73 | MEN1 (0.54) | PTGESBACE1MAPTMEN1KMT2A | |
| SCHEMBL30061165 | 0.73 | MEN1 (0.54) | PTGESBACE1MAPTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7160887-B1 | Aromatic amine derivatives, their production and use | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2007-01-09 | — | — | US | disclosed |