Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | DAGLA | Q9Y4D2 | 1/20 | 0.40 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.40 |
| ▸ | CETP | P11597 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | HTR6 | P50406 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | PTGES | O14684 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5205997 | 0.85 | PTGES (0.45) | MAPTPOLBCETPMEN1KMT2A | |
| SCHEMBL5206121 | 0.83 | MEN1 (0.41) | DAGLAMEN1KMT2AHTTL3MBTL1 | |
| SCHEMBL14674831 | 0.81 | TBXA2R (0.42) | TDP1MAPTTBXA2RMEN1KMT2A | |
| SCHEMBL5202463 | 0.79 | TDP1 (0.42) | TDP1MAPTPOLBTBXA2RMEN1 | |
| SCHEMBL5202456 | 0.79 | TDP1 (0.42) | TDP1MAPTPOLBTBXA2RMEN1 | |
| SCHEMBL6178811 | 0.78 | HPGD (0.51) | TDP1MAPTPOLBMEN1KMT2A | |
| SCHEMBL14673865 | 0.78 | MAPT (0.44) | MAPTPOLBCETPMEN1KMT2A | |
| SCHEMBL5205566 | 0.77 | TDP1 (0.41) | TDP1MAPTTBXA2RMEN1KMT2A | |
| SCHEMBL5201497 | 0.77 | TDP1 (0.41) | TDP1MAPTTBXA2RMEN1KMT2A | |
| SCHEMBL5355976 | 0.77 | PDE7A (0.47) | TDP1MAPTMEN1KMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7160887-B1 | Aromatic amine derivatives, their production and use | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2007-01-09 | — | — | US | disclosed |