Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | LTA4H | P09960 | 1/20 | 0.44 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.44 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.43 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.43 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.43 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5206544 | 0.80 | MEN1 (0.45) | ALDH1A1HTTLMNAL3MBTL1KMT2A | |
| SCHEMBL5205997 | 0.78 | PTGES (0.45) | PTGS1PTGS2POLBMAPTKMT2A | |
| SCHEMBL5201443 | 0.78 | SRD5A2 (0.52) | ALDH1A1HTTESR2LTA4HPTGS1 | |
| SCHEMBL14674248 | 0.78 | LPAR1 (0.44) | LPAR1LPAR5 | |
| SCHEMBL5206028 | 0.77 | MAPK1 (0.57) | ALDH1A1HTTLMNAL3MBTL1POLB | |
| SCHEMBL5206034 | 0.77 | MAPK1 (0.57) | ALDH1A1HTTLMNAL3MBTL1POLB | |
| SCHEMBL5204827 | 0.76 | TDP1 (0.41) | HTTLMNAL3MBTL1POLBMAPT | |
| SCHEMBL14674209 | 0.76 | MAPT (0.41) | ALDH1A1HTTLMNAPOLBMAPT | |
| SCHEMBL6178891 | 0.75 | HPGD (0.54) | ALDH1A1HTTESR2LMNALTA4H | |
| SCHEMBL5204961 | 0.75 | L3MBTL1 (0.51) | ALDH1A1HTTLTA4HPTGS1PTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7160887-B1 | Aromatic amine derivatives, their production and use | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2007-01-09 | — | — | US | disclosed |