Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP1 | P03956 | 1/20 | 0.44 |
| ▸ | MMP2 | P08253 | 1/20 | 0.44 |
| ▸ | MMP3 | P08254 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | TAS1R3 | Q7RTX0 | 2/20 | 0.40 |
| ▸ | TAS1R1 | Q7RTX1 | 2/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5205427 | 0.88 | MMP1 (0.41) | MMP1MMP2MMP3SMN1; SMN2PKM | |
| SCHEMBL5209088 | 0.83 | MMP1 (0.47) | MMP1MMP2MMP3SMN1; SMN2PKM | |
| SCHEMBL22616345 | 0.83 | TSHR (0.48) | MMP1MMP2TAS1R3TAS1R1CA12 | |
| SCHEMBL5209301 | 0.81 | TAS1R3 (0.48) | MMP1MMP2SMN1; SMN2PKMTAS1R3 | |
| SCHEMBL4895396 | 0.81 | TAS1R3 (0.40) | TAS1R3TAS1R1KMT2AMEN1ALDH1A1 | |
| SCHEMBL4907353 | 0.80 | TAS1R3 (0.62) | MMP1MMP2MMP3SMN1; SMN2PKM | |
| SCHEMBL5203991 | 0.80 | TAS1R3 (0.37) | TAS1R3TAS1R1 | |
| SCHEMBL4907351 | 0.80 | TAS1R3 (0.62) | MMP1MMP2MMP3SMN1; SMN2PKM | |
| SCHEMBL4889332 | 0.79 | TAS1R3 (0.39) | TAS1R3TAS1R1 | |
| SCHEMBL5209568 | 0.79 | TAS1R3 (0.36) | TAS1R3TAS1R1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0958292-B1 | 4-(3-HETEROCYCLYL-1-BENZOYL)PYRAZOLES AND THEIR USE AS HERBICIDES | BASF AG (DE) | 2007-01-03 | — | — | EP | disclosed |
| US-6165944-A | 4-(3-heterocyclyl-1-benzoyl) pyrazoles and their use as herbicides | BASF AKTIENGESELLSCHAFT (DE) | 2000-12-26 | — | — | US | disclosed |