SCHEMBL5209568

SCHEMBL5209568

CCC[CH]C(=O)NC(CC)C(C)CC

nearest known ligand 0.36

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
TAS1R3 Q7RTX0 1/20 0.36
TAS1R1 Q7RTX1 1/20 0.36
ALDH1A1 P00352 1/20 0.33
MME P08473 1/20 0.33
ACE P12821 1/20 0.33
CPA1 P15085 1/20 0.33
ACE2 Q9BYF1 1/20 0.33
FAAH O00519 1/20 0.30
CNR1 P21554 1/20 0.30
CNR2 P34972 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5203991 0.87 TAS1R3 (0.37) TAS1R3TAS1R1FAAHCNR1CNR2
SCHEMBL5211819 0.85 ALDH1A1 (0.35) ALDH1A1MMEACECPA1ACE2
SCHEMBL5206148 0.79 MMP1 (0.44) TAS1R3TAS1R1ALDH1A1
SCHEMBL5210941 0.79 ALDH1A1 (0.36) ALDH1A1MMEACECPA1ACE2
SCHEMBL22616345 0.78 TSHR (0.48) TAS1R3TAS1R1ALDH1A1FAAHCNR1
SCHEMBL4895396 0.76 TAS1R3 (0.40) TAS1R3TAS1R1ALDH1A1FAAHCNR1
SCHEMBL5209301 0.76 TAS1R3 (0.48) TAS1R3TAS1R1
SCHEMBL4889332 0.75 TAS1R3 (0.39) TAS1R3TAS1R1
SCHEMBL5208342 0.73 TAS1R3 (0.42) TAS1R3TAS1R1ALDH1A1
SCHEMBL24855310 0.71 ALDH1A1 (0.39) ALDH1A1MMEACECPA1ACE2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0958292-B1 4-(3-HETEROCYCLYL-1-BENZOYL)PYRAZOLES AND THEIR USE AS HERBICIDES BASF AG (DE) 2007-01-03 EP disclosed
US-6165944-A 4-(3-heterocyclyl-1-benzoyl) pyrazoles and their use as herbicides BASF AKTIENGESELLSCHAFT (DE) 2000-12-26 US disclosed
EP-0958292-A1 4-(3-HETEROCYCLYL-1-BENZOYL)PYRAZOLES AND THEIR USE AS HERBICIDES BASF AKTIENGESELLSCHAFT (DE) 1999-11-24 EP disclosed
WO-1998031682-A1 4-(3-HETEROCYCLYL-1-BENZOYL)PYRAZOLES AND THEIR USE AS HERBICIDES BASF AKTIENGESELLSCHAFT (DE) 1998-07-23 WO disclosed