Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.55 |
| ▸ | POLB | P06746 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 3/20 | 0.44 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.44 |
| ▸ | CDK8 | P49336 | 1/20 | 0.42 |
| ▸ | CDK19 | Q9BWU1 | 1/20 | 0.42 |
| ▸ | COMT | P21964 | 1/20 | 0.38 |
| ▸ | P2RY1 | P47900 | 1/20 | 0.37 |
| ▸ | LIMK1 | P53667 | 3/20 | 0.35 |
| ▸ | IKBKB | O14920 | 2/20 | 0.35 |
| ▸ | CHUK | O15111 | 1/20 | 0.34 |
| ▸ | PRKACA | P17612 | 1/20 | 0.34 |
| ▸ | PRKACG | P22612 | 1/20 | 0.34 |
| ▸ | PRKACB | P22694 | 1/20 | 0.34 |
| ▸ | BTK | Q06187 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL975710 | 0.83 | MAPT (0.60) | MAPTPOLBALDH1A1KDM4EHTT | |
| SCHEMBL14269337 | 0.83 | MAPT (0.56) | MAPTPOLBALDH1A1KDM4EHTT | |
| SCHEMBL2199155 | 0.81 | MAPT (0.56) | MAPTPOLBALDH1A1KDM4EHTT | |
| SCHEMBL16217224 | 0.80 | MAPT (0.54) | MAPTPOLBALDH1A1KDM4EHTT | |
| SCHEMBL20782350 | 0.79 | CDK8 (0.37) | MAPTPOLBALDH1A1KDM4EHTT | |
| SCHEMBL11330712 | 0.79 | ALDH1A1 (0.41) | MAPTPOLBALDH1A1CDK8CDK19 | |
| SCHEMBL12883301 | 0.79 | MAPT (0.52) | MAPTPOLBALDH1A1KDM4EHTT | |
| SCHEMBL13544346 | 0.79 | MAPT (0.52) | MAPTPOLBALDH1A1KDM4EHTT | |
| SCHEMBL7988803 | 0.79 | MAPT (0.52) | MAPTPOLBALDH1A1KDM4EHTT | |
| SCHEMBL8551963 | 0.78 | MEN1 (0.48) | MAPTPOLBALDH1A1KDM4EHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 34 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108440444-B | 2-methyl-4-trifluoromethyl-5-thiazole formamide compound | 江苏再拓生物科技有限公司 | 2021-01-19 | — | — | CN | claimed |
| CN-111233787-A | Green pesticide composition and preparation method thereof | 湖南博隽生物医药有限公司 | 2020-06-05 | — | — | CN | claimed |
| CN-111226949-A | Environment-friendly plant bactericide | 湖南博隽生物医药有限公司 | 2020-06-05 | — | — | CN | claimed |
| CN-108440444-A | 2-methyl-4-trifluoromethyl-5-thiazole formamide compound | 湖南博隽生物医药有限公司 | 2018-08-24 | — | — | CN | claimed |
| US-9382197-B2 | Substituted hydroxamic acids and uses thereof | MILLENNIUM PHARMACEUTICALS, INC. (US) | 2016-07-05 | — | — | US | claimed |
| CN-1069902-C | Thifluzamide with stabilized efficacy | ROHM & HAAS (US) | 2001-08-22 | — | — | CN | claimed |
| CN-118420560-A | Synthesis method of 2- (trifluoromethyl) -4, 5-disubstituted thiazole compound | 西北师范大学 | 2024-08-02 | — | — | CN | disclosed |
| CN-112204009-B | Modulators of integrated stress pathways | 卡里科生命科学有限责任公司 | 2024-05-07 | — | — | CN | disclosed |
| CN-117551037-A | Compounds as succinate dehydrogenase inhibitors and uses thereof | 华东理工大学 | 2024-02-13 | — | — | CN | disclosed |
| CN-109641854-B | Modulators of integrated stress pathways | 卡里科生命科学有限责任公司 | 2023-02-03 | — | — | CN | disclosed |
| CN-109195965-B | Inhibitors of WDR5 protein-protein binding | 普罗佩纶治疗公司 | 2022-07-26 | — | — | CN | disclosed |
| CN-108440444-B | 2-methyl-4-trifluoromethyl-5-thiazole formamide compound | 江苏再拓生物科技有限公司 | 2021-01-19 | — | — | CN | disclosed |
| CN-111226949-A | Environment-friendly plant bactericide | 湖南博隽生物医药有限公司 | 2020-06-05 | — | — | CN | disclosed |
| US-20050215495-A1 | Macrolide antibiotics | ALIHODZIC SULEJMAN | 2005-09-29 | — | — | US | disclosed |
| US-20040077557-A1 | Macrolide antibiotics | GLAXO GROUP LIMITED (GB) | 2004-04-22 | — | — | US | disclosed |
| EP-1363925-A1 | MACROLIDE ANTIBIOTICS | GLAXO GROUP LIMITED (GB) | 2003-11-26 | — | — | EP | disclosed |
| WO-2002050091-A1 | MACROLIDE ANTIBIOTICS | GLAXO GROUP LIMITED (GB) | 2002-06-27 | — | — | WO | disclosed |
| CN-1338452-A | Substituted phenylamine derivatives | MITSUI CHEMICALS INC (JP) | 2002-03-06 | — | — | CN | disclosed |
| CN-1067063-C | Substituted carboxanilide derivatives and plant disease control agents containing the same as active ingredient | MITSUI TOATSU CHEMICALS (JP) | 2001-06-13 | — | — | CN | disclosed |
| CN-1178791-A | Substituted carboxanilide derivatives and plant disease control agents containing the same as active ingredient | MITSUI TOATSU CHEMICALS (JP) | 1998-04-15 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050215495-A1 | Macrolide antibiotics | IL1R1, MRPL12, RPS21 | MAPT 3557/4885POLB 2625/4885ALDH1A1 2549/4885 |
| US-20040077557-A1 | Macrolide antibiotics | MALT1, MRPL21, IL1R1 | MAPT 3349/4885POLB 2847/4885ALDH1A1 2482/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.