Sugi Predict

Sugi Predict / Compounds / SCHEMBL975710

SCHEMBL975710

SCHEMBL975710

Cc1nc(C(F)(F)F)c(C(=O)O)s1

nearest known ligand 0.60

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
▸ MAPT P10636 4/20 0.60
▸ ALDH1A1 P00352 3/20 0.57
▸ POLB P06746 3/20 0.56
▸ HSD11B1 P28845 1/20 0.45
▸ GAA P10253 1/20 0.45
▸ HPGD P15428 1/20 0.44
▸ TSHR P16473 1/20 0.44
▸ SMN1; SMN2 Q16637 5/20 0.43
▸ KDM4E B2RXH2 2/20 0.43
▸ HTT P42858 1/20 0.43
▸ TDP1 Q9NUW8 1/20 0.43
▸ COMT P21964 1/20 0.39
▸ RAB9A P51151 3/20 0.36
▸ NPC1 O15118 2/20 0.36
▸ RECQL P46063 1/20 0.36
▸ L3MBTL1 Q9Y468 1/20 0.35
▸ GPR35 Q9HC97 1/20 0.35
▸ MEN1 O00255 1/20 0.35
▸ KMT2A Q03164 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14269337 0.85 MAPT (0.56) MAPTALDH1A1POLBHSD11B1GAA
SCHEMBL28054759 0.84 MAPT (0.48) MAPTALDH1A1POLBHSD11B1GAA
SCHEMBL5206178 0.83 MAPT (0.55) MAPTALDH1A1POLBHSD11B1GAA
SCHEMBL2199155 0.83 MAPT (0.56) MAPTALDH1A1POLBHSD11B1GAA
SCHEMBL9643932 0.82 ALDH1A1 (0.46) MAPTALDH1A1POLBGAAHPGD
SCHEMBL16217224 0.81 MAPT (0.54) MAPTALDH1A1POLBHSD11B1GAA
SCHEMBL9642810 0.81 ALDH1A1 (0.48) MAPTALDH1A1POLBGAAHPGD
SCHEMBL13544346 0.80 MAPT (0.52) MAPTALDH1A1POLBHSD11B1GAA
SCHEMBL12883301 0.80 MAPT (0.52) MAPTALDH1A1POLBHSD11B1GAA
SCHEMBL7988803 0.80 MAPT (0.52) MAPTALDH1A1POLBHSD11B1GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 247 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119591560-B Synthesis method of thifluzamide 湖南速博生物技术有限公司 2025-04-29 — — CN claimed
CN-119591560-A Synthesis method of thifluzamide 湖南速博生物技术有限公司 2025-03-11 — — CN claimed
CN-115611814-B Compound containing 2-amino imidazole ring, and preparation method and application thereof 烟台新药创制山东省实验室 2024-11-19 — — CN claimed
CN-118599399-B Anticorrosive powder coating for fire-fighting pipeline and preparation method thereof 浙江捷宇新材料科技股份有限公司 2024-11-12 — — CN claimed
CN-117024088-B High-corrosion-resistance concrete and preparation method thereof 桐庐鼎力建材有限公司 2024-09-24 — — CN claimed
CN-118599399-A Anticorrosive powder coating for fire-fighting pipeline and preparation method thereof 浙江捷宇新材料科技股份有限公司 2024-09-06 — — CN claimed
CN-117024088-A High-corrosion-resistance concrete and preparation method thereof 桐庐鼎力建材有限公司 2023-11-10 — — CN claimed
CN-116903821-A Aliphatic polyurethane resin with high wear resistance and high heat resistance and preparation method thereof 浙江禾欣科技有限公司 2023-10-20 — — CN claimed
CN-116694193-A High weather-resistant and high chemical corrosion-resistant epoxy powder coating and preparation method thereof 浙江捷宇新材料科技股份有限公司 2023-09-05 — — CN claimed
CN-116354902-A Green and environment-friendly process for synthesizing 2-methyl-4-trifluoromethyl-5-thiazole formic acid 广东禾康精细化工有限公司 2023-06-30 — — CN claimed
US-20100298313-A1 METHOD OF USING IMIDAZOLOTHIAZOLE COMPOUNDS FOR THE TREATMENT OF DISEASE AMBIT BIOSCIENCES CORPORATION 2010-11-25 — — US claimed
US-7820657-B2 receptor kinase inhibitors such as 3-(2-{4-[3-(5-tert-Butyl-isoxazol-3-yl)-ureido]-phenyl}-benzo[d]imidazo[2,1-b]thiazol-7-yl)-N-(2-morpholin-4-yl-ethyl)-propionamide; flk inhibitors AMBIT BIOSCIENCES CORPORATION (US) 2010-10-26 — — US claimed
EP-2001892-A2 IMIDAZOLOTHIAZOLE COMPOUNDS FOR THE TREATMENT OF DISEASE Ambit Biosciences Corporation (US) 2008-12-17 — — EP claimed
US-20070232604-A1 receptor kinase inhibitors such as 3-(2-{4-[3-(5-tert-Butyl-isoxazol-3-yl)-ureido]-phenyl}-benzo[d]imidazo[2,1-b]thiazol-7-yl)-N-(2-morpholin-4-yl-ethyl)-propionamide; flk inhibitors AMBIT BIOSCIENCES CORPORATION 2007-10-04 — — US claimed
WO-2007109120-A2 IMIDAZOLOTHIAZOLE COMPOUNDS FOR THE TREATMENT OF DISEASE AMBIT BIOSCIENCES CORPORATION (US) 2007-09-27 — — WO claimed
CN-1049656-C Improved process for the preparing of 2-methylthiazole-5-carboxylates ROHM & HAAS (US) 2000-02-23 — — CN claimed
US-5880288-A Process for the preparation of 2-methylthiazole-5-carboxylates ROHM AND HAAS COMPANY (US) 1999-03-09 — — US claimed
EP-0607795-B1 Process for the preparation of 2-alkyl-4-fluoromethyl-thiazole-carboxylic acid esters BASF AG (DE) 1995-10-04 — — EP claimed
CN-1102410-A Improved process for the preparing of 2-methylthiazole-5-carboxylates MONSANTO CO (US) 1995-05-10 — — CN claimed
EP-0650963-A1 Improved process for the preparation of 2-methylthiazole-5-carboxylates ROHM AND HAAS COMPANY (US) 1995-05-03 — — EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100298313-A1 METHOD OF USING IMIDAZOLOTHIAZOLE COMPOUNDS FOR THE TREATMENT OF DISEASE GRK2, GRK4, GRK5 MAPT 1392/4885ALDH1A1 3615/4885POLB 2100/4885
US-20070232604-A1 receptor kinase inhibitors such as 3-(2-{4-[3-(5-tert-Butyl-isoxazol-3-yl)-ureido]-phenyl}-benzo[d]imidazo[2,1-b]thiazol-7-yl)-N-(2-morpholin-4-yl-ethyl)-propionamide; flk inhibitors GRK2, GRK3, BLK MAPT 1520/4885ALDH1A1 3405/4885POLB 3371/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.