Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | SRC | P12931 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | ERN1 | O75460 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | TUBB4A | P04350 | 3/20 | 0.34 |
| ▸ | TUBB | P07437 | 3/20 | 0.34 |
| ▸ | TUBA3C | P0DPH7 | 3/20 | 0.34 |
| ▸ | TUBA1B | P68363 | 3/20 | 0.34 |
| ▸ | TUBA4A | P68366 | 3/20 | 0.34 |
| ▸ | TUBB4B | P68371 | 3/20 | 0.34 |
| ▸ | TUBB3 | Q13509 | 3/20 | 0.34 |
| ▸ | TUBB2A | Q13885 | 3/20 | 0.34 |
| ▸ | TUBB8 | Q3ZCM7 | 3/20 | 0.34 |
| ▸ | TUBA3E | Q6PEY2 | 3/20 | 0.34 |
| ▸ | TUBA1A | Q71U36 | 3/20 | 0.34 |
| ▸ | TUBA1C | Q9BQE3 | 3/20 | 0.34 |
| ▸ | TUBB6 | Q9BUF5 | 3/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5231515 | 0.86 | MAPT (0.35) | ERN1MAPTCYP3A4NPSR1TUBB4A | |
| SCHEMBL5207796 | 0.83 | CYP3A4 (0.52) | ERN1MAPTCYP3A4TUBB4ATUBB | |
| SCHEMBL4116122 | 0.78 | GAA (0.40) | GAASRCALDH1A1ERN1MAPT | |
| SCHEMBL5205549 | 0.75 | HTR2A (0.49) | SRCALDH1A1MAPTTUBB4ATUBB | |
| SCHEMBL5203371 | 0.75 | CYP1A2 (0.43) | ALDH1A1ERN1MAPTCYP3A4TUBB4A | |
| SCHEMBL6628469 | 0.75 | RXFP1 (0.39) | ALDH1A1ERN1MAPTCYP3A4NPSR1 | |
| SCHEMBL5206460 | 0.73 | CA12 (0.35) | GAAALDH1A1ERN1MAPTCYP3A4 | |
| SCHEMBL5206042 | 0.73 | CA12 (0.35) | ALDH1A1ERN1MAPTCYP3A4NPSR1 | |
| SCHEMBL178390 | 0.72 | ACHE (0.50) | MAPTCYP3A4TUBB4ATUBBTUBA3C | |
| SCHEMBL5208220 | 0.72 | SMN1; SMN2 (0.48) | GAAALDH1A1ERN1MAPTTUBB4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1403250-B1 | BIS(5-ARYL-2-PYRIDYL) DERIVATIVE | KOWA CO (JP) | 2007-07-18 | — | — | EP | disclosed |
| EP-1403251-B1 | BIS(2-ARYL-5-PYRIDYL) DERIVATIVE | KOWA CO (JP) | 2007-07-18 | — | — | EP | disclosed |
| EP-1403250-A1 | BIS(5-ARYL-2-PYRIDYL) DERIVATIVE | Kowa Co., Ltd. (JP) | 2004-03-31 | — | — | EP | disclosed |
| EP-1403251-A1 | BIS(2-ARYL-5-PYRIDYL) DERIVATIVE | Kowa Co., Ltd. (JP) | 2004-03-31 | — | — | EP | disclosed |