Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | PPARG | P37231 | 6/20 | 0.39 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | HTR2A | P28223 | 1/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5202456 | 0.83 | TDP1 (0.42) | PPARGMRGPRX4PKMLMNAMAPT | |
| SCHEMBL5202463 | 0.83 | TDP1 (0.42) | PPARGMRGPRX4PKMLMNAMAPT | |
| SCHEMBL5206343 | 0.80 | L3MBTL1 (0.43) | L3MBTL1PPARGMRGPRX4CYP1A2CYP3A4 | |
| SCHEMBL6177342 | 0.80 | L3MBTL1 (0.45) | L3MBTL1PPARGMRGPRX4CYP1A2CYP3A4 | |
| SCHEMBL6177713 | 0.78 | L3MBTL1 (0.43) | L3MBTL1PPARGMRGPRX4CYP1A2CYP3A4 | |
| SCHEMBL5206121 | 0.77 | MEN1 (0.41) | L3MBTL1PPARGMRGPRX4CYP1A2CYP3A4 | |
| SCHEMBL5206332 | 0.76 | ALOX5 (0.44) | L3MBTL1PPARGMRGPRX4CYP1A2CYP3A4 | |
| SCHEMBL2398857 | 0.70 | CYP3A4 (0.73) | L3MBTL1CYP1A2CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL5206336 | 0.69 | L3MBTL1 (0.41) | L3MBTL1PPARGMRGPRX4CYP1A2CYP3A4 | |
| SCHEMBL6178518 | 0.68 | PTGER4 (0.50) | L3MBTL1MRGPRX4CYP1A2CYP3A4CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7160887-B1 | Aromatic amine derivatives, their production and use | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2007-01-09 | — | — | US | disclosed |