Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.42 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 5/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | TTR | P02766 | 2/20 | 0.39 |
| ▸ | PPOX | P50336 | 1/20 | 0.39 |
| ▸ | F10 | P00742 | 1/20 | 0.37 |
| ▸ | HTR6 | P50406 | 1/20 | 0.37 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.37 |
| ▸ | ALB | P02768 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.37 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.37 |
| ▸ | PPARG | P37231 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.35 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5202456 | 1.00 | TDP1 (0.42) | TDP1TBXA2RMEN1KMT2AMAPT | |
| SCHEMBL5206439 | 0.83 | L3MBTL1 (0.41) | TBXA2RMAPTLMNAMRGPRX4PPARG | |
| SCHEMBL5201504 | 0.82 | TDP1 (0.47) | TDP1TBXA2RMEN1KMT2AMAPT | |
| SCHEMBL6180524 | 0.82 | TDP1 (0.47) | TDP1TBXA2RMEN1KMT2AMAPT | |
| SCHEMBL6180530 | 0.82 | TDP1 (0.47) | TDP1TBXA2RMEN1KMT2AMAPT | |
| SCHEMBL6177157 | 0.79 | TDP1 (0.43) | TDP1TBXA2RMEN1KMT2AMAPT | |
| SCHEMBL5204827 | 0.79 | TDP1 (0.41) | TDP1TBXA2RMEN1KMT2AMAPT | |
| SCHEMBL5205566 | 0.78 | TDP1 (0.41) | TDP1TBXA2RMEN1KMT2AMAPT | |
| SCHEMBL5201497 | 0.78 | TDP1 (0.41) | TDP1TBXA2RMEN1KMT2AMAPT | |
| SCHEMBL9174802 | 0.74 | MEN1 (0.60) | TDP1MEN1KMT2AMAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7160887-B1 | Aromatic amine derivatives, their production and use | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2007-01-09 | — | — | US | disclosed |