Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCG2 | Q9UNQ0 | 2/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.47 |
| ▸ | RAB9A | P51151 | 4/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 2/20 | 0.46 |
| ▸ | ADCY8 | P40145 | 2/20 | 0.45 |
| ▸ | ADCY1 | Q08828 | 2/20 | 0.45 |
| ▸ | MYC | P01106 | 1/20 | 0.45 |
| ▸ | MAX | P61244 | 1/20 | 0.45 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.44 |
| ▸ | CFTR | P13569 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5207718 | 0.86 | KDM4E (0.51) | ABCG2SMN1; SMN2RAB9ANPSR1KDM4E | |
| SCHEMBL5203117 | 0.86 | ABCG2 (0.58) | ABCG2SMN1; SMN2RAB9ANPSR1KDM4E | |
| SCHEMBL5202688 | 0.83 | MYC (0.58) | ABCG2SMN1; SMN2RAB9ANPSR1KDM4E | |
| SCHEMBL26915315 | 0.80 | RAB9A (0.52) | ABCG2SMN1; SMN2RAB9ANPSR1KDM4E | |
| SCHEMBL2484166 | 0.80 | KDM4E (0.51) | SMN1; SMN2RAB9ANPSR1KDM4EHPGD | |
| SCHEMBL16107684 | 0.77 | CFTR (0.54) | KDM4EHPGDTDP1HSD17B10ALDH1A1 | |
| SCHEMBL5203249 | 0.77 | S1PR1 (0.61) | SMN1; SMN2RAB9AKDM4EHPGDNPC1 | |
| SCHEMBL12255362 | 0.75 | KDM4E (0.47) | SMN1; SMN2RAB9ANPSR1KDM4EHPGD | |
| SCHEMBL968069 | 0.74 | SMN1; SMN2 (0.59) | SMN1; SMN2RAB9AKDM4EHPGDNPC1 | |
| SCHEMBL967102 | 0.74 | SMN1; SMN2 (0.59) | SMN1; SMN2RAB9AKDM4EHPGDNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7223791-B2 | Function regulator for retinoid relative receptor | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2007-05-29 | — | — | US | disclosed |
| US-20040157881-A1 | Function regulator for retinoid relative receptor | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2004-08-12 | — | — | US | disclosed |
| EP-1405636-A1 | FUNCTION REGULATOR FOR RETINOID RELATIVE RECEPTOR | Takeda Chemical Industries, Ltd. (JP) | 2004-04-07 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040157881-A1 | Function regulator for retinoid relative receptor | RXRA, RARA, RARG | ABCG2 1644/4885SMN1; SMN2 4686/4885RAB9A 1448/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.