Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 10/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.56 |
| ▸ | HPGD | P15428 | 4/20 | 0.56 |
| ▸ | HTR6 | P50406 | 2/20 | 0.53 |
| ▸ | TUBB4A | P04350 | 3/20 | 0.52 |
| ▸ | TUBB | P07437 | 3/20 | 0.52 |
| ▸ | TUBA3C | P0DPH7 | 3/20 | 0.52 |
| ▸ | TUBA1B | P68363 | 3/20 | 0.52 |
| ▸ | TUBA4A | P68366 | 3/20 | 0.52 |
| ▸ | TUBB4B | P68371 | 3/20 | 0.52 |
| ▸ | TUBB3 | Q13509 | 3/20 | 0.52 |
| ▸ | TUBB2A | Q13885 | 3/20 | 0.52 |
| ▸ | TUBB8 | Q3ZCM7 | 3/20 | 0.52 |
| ▸ | TUBA3E | Q6PEY2 | 3/20 | 0.52 |
| ▸ | TUBA1A | Q71U36 | 3/20 | 0.52 |
| ▸ | TUBA1C | Q9BQE3 | 3/20 | 0.52 |
| ▸ | TUBB6 | Q9BUF5 | 3/20 | 0.52 |
| ▸ | TUBB2B | Q9BVA1 | 3/20 | 0.52 |
| ▸ | TUBB1 | Q9H4B7 | 3/20 | 0.52 |
| ▸ | MAPT | P10636 | 3/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2205697 | 0.85 | KDM4E (0.57) | KDM4EALDH1A1HPGDHTR6TUBB4A | |
| SCHEMBL7674774 | 0.82 | ALDH1A1 (0.57) | KDM4EALDH1A1HPGDHTR6TUBB4A | |
| SCHEMBL24074556 | 0.82 | MAPT (0.60) | KDM4EALDH1A1HPGDHTR6TUBB4A | |
| SCHEMBL31396873 | 0.81 | KDM4E (0.53) | KDM4EALDH1A1HPGDHTR6TUBB4A | |
| SCHEMBL2810876 | 0.81 | ALDH1A1 (0.58) | KDM4EALDH1A1HPGDHTR6TUBB4A | |
| SCHEMBL24487440 | 0.80 | KDM4E (0.55) | KDM4EALDH1A1HPGDHTR6TUBB4A | |
| SCHEMBL2956667 | 0.79 | ALDH1A1 (0.73) | KDM4EALDH1A1HPGDHTR6TUBB4A | |
| SCHEMBL5206974 | 0.77 | ALDH1A1 (0.54) | KDM4EALDH1A1HPGDHTR6TUBB4A | |
| SCHEMBL24487443 | 0.77 | HTR6 (0.61) | KDM4EALDH1A1HPGDHTR6TUBB4A | |
| SCHEMBL31396902 | 0.76 | MAPT (0.53) | KDM4EALDH1A1HPGDHTR6TUBB4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1765775-A1 | INDOLES USEFUL IN THE TREATMENT OF INFLAMMATION | Biolipox AB (SE) | 2007-03-28 | — | — | EP | disclosed |
| WO-2005123675-A1 | INDOLES USEFUL IN THE TREATMENT OF INFLAMMATION | BIOLIPOX AB (SE) | 2005-12-29 | — | — | WO | disclosed |