SCHEMBL5207256

SCHEMBL5207256

C=CC(=O)NC(CC)OC

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 6/20 0.48
ALDH1A1 P00352 3/20 0.37
MAPK1 P28482 1/20 0.37
TDP1 Q9NUW8 1/20 0.37
ACACB O00763 2/20 0.36
ZDHHC20 Q5W0Z9 1/20 0.36
ZDHHC2 Q9UIJ5 1/20 0.36
CYP2C19 P33261 2/20 0.33
TGM2 P21980 1/20 0.33
MMP1 P03956 2/20 0.31
MMP2 P08253 2/20 0.31
CA12 O43570 1/20 0.31
CA1 P00915 1/20 0.31
CA2 P00918 1/20 0.31
MMP8 P22894 1/20 0.31
CA9 Q16790 1/20 0.31
PSMB11 A5LHX3 1/20 0.31
PSMA7 O14818 1/20 0.31
PSMB1 P20618 1/20 0.31
PSMA1 P25786 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10487230 0.87 TSHR (0.48) TSHRALDH1A1MAPK1TDP1ACACB
SCHEMBL2847929 0.85 TSHR (0.45) TSHRALDH1A1MAPK1TDP1ACACB
SCHEMBL6580192 0.82 TSHR (0.47) TSHRALDH1A1MAPK1TDP1ACACB
SCHEMBL18124154 0.81 TSHR (0.50) TSHRALDH1A1MAPK1TDP1ACACB
SCHEMBL28257876 0.79 TSHR (0.44) TSHRALDH1A1MAPK1TDP1ACACB
SCHEMBL27661507 0.79 TSHR (0.40) TSHRALDH1A1MAPK1TDP1ACACB
SCHEMBL3884328 0.77 TSHR (0.45) TSHRALDH1A1MAPK1TDP1ACACB
SCHEMBL20530419 0.77 TSHR (0.41) TSHRALDH1A1MAPK1TDP1ACACB
SCHEMBL11382557 0.76 MMP1 (0.37) TSHRALDH1A1MAPK1MMP1MMP2
SCHEMBL21368259 0.74 TSHR (0.47) TSHRALDH1A1MAPK1TDP1ACACB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 56 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117986426-A Preparation method of emulsifier for waterproof emulsion 南通腾龙化工科技有限公司 2024-05-07 CN claimed
CN-115260389-A Anionic crosslinked polymer and preparation method thereof 广州华淼生物科技研究院有限公司 2022-11-01 CN claimed
EP-3200840-B1 LOW-WATER CONTENT ACRYLATE-ACRYLAMIDE COPOLYMERS FOR OPHTHALMIC DEVICES ALCON INC (CH) 2021-11-17 EP claimed
CN-106999629-B Low water content acrylate-acrylamide copolymers for ophthalmic devices 诺华股份有限公司 2020-02-21 CN claimed
EP-2310104-B1 MIXED GRAFT POLYMERS FOR ION EXCHANGE CHROMATOGRAPHY MERCK PATENT GMBH (DE) 2017-10-18 EP claimed
EP-3200840-A1 LOW-WATER CONTENT ACRYLATE-ACRYLAMIDE COPOLYMERS FOR OPHTHALMIC DEVICES Novartis AG (CH) 2017-08-09 EP claimed
CN-106999629-A Low water content acrylate acrylamide copolymer for Ophthalmoligic instrument 诺华股份有限公司 2017-08-01 CN claimed
EP-2267048-B1 FLUOROPOLYMER AND WATER-REPELLENT AND OIL-REPELLENT AGENT DAIKIN IND LTD (JP) 2016-10-12 EP claimed
WO-2016100190-A1 LOW-WATER CONTENT ACRYLATE-ACRYLAMIDE COPOLYMERS FOR OPHTHALMIC DEVICES NOVARTIS AG (CH) 2016-06-23 WO claimed
CN-102112191-B Graft copolymers for ion exchange chromatography MERCK PATENT GMBH 2014-07-30 CN claimed
CN-102112191-A Graft copolymers for ion exchange chromatography MERCK PATENT GMBH 2011-06-29 CN claimed
EP-1829611-A1 Alkali-stable hydrophilic sorbents for ion-exchange chromatography Merck Patent GmbH (DE) 2007-09-05 EP claimed
JP-61225157-A None JP disclosed
CN-120005093-A Polymeric excipients for biopharmaceutical formulations 小利兰斯坦福大学董事会 2025-05-16 CN disclosed
CN-115698106-B Polymeric excipients for biopharmaceutical formulations 小利兰斯坦福大学董事会 2025-01-07 CN disclosed
CN-116836345-A Polymer particles having gradient composition and method for producing same 沃特世科技公司 2023-10-03 CN disclosed
US-5880237-A POLYACRYLIC AMIDES FOR BINDING CERAMICS NALCO CHEMICAL COMPANY (US) 1999-03-09 US disclosed
US-5726267-A POLYETHER-ACRYLIC AMIDE COPOLYMERS, BINDERS FOR CERAMICS, LOW VISCOSITY NALCO CHEMICAL COMPANY (US) 1998-03-10 US disclosed
EP-0692506-A2 Thermo-sensitive polyether polyurethane, production method thereof and thermo-sensitive composition MIYOSHI YUSHI KABUSHIKI KAISHA (JP) 1996-01-17 EP disclosed
JP-S61225157-A NOVEL VINYL COMPOUND AGENCY OF IND SCIENCE & TECHNOL 1986-10-06 JP disclosed