Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | CACNA1G | O43497 | 3/20 | 0.45 |
| ▸ | MAPT | P10636 | 8/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.39 |
| ▸ | USP2 | O75604 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | KDR | P35968 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | CETP | P11597 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5213773 | 0.92 | PIK3CA (0.41) | MAPTSMN1; SMN2ALDH1A1MEN1KMT2A | |
| SCHEMBL5213026 | 0.88 | CHRM1 (0.38) | L3MBTL1CACNA1GMAPTSMN1; SMN2GAA | |
| SCHEMBL5215328 | 0.86 | RAB9A (0.41) | LMNACACNA1GMAPTSMN1; SMN2ALDH1A1 | |
| SCHEMBL5208383 | 0.85 | SMO (0.43) | MAPTSMN1; SMN2ALDH1A1MEN1POLB | |
| SCHEMBL5207015 | 0.84 | MAPT (0.41) | LMNAMAPTSMN1; SMN2HTTMEN1 | |
| SCHEMBL5207380 | 0.84 | LMNA (0.45) | LMNAL3MBTL1CACNA1GMAPTSMN1; SMN2 | |
| SCHEMBL5212795 | 0.84 | CNR2 (0.35) | LMNAMAPTMEN1POLBKMT2A | |
| SCHEMBL5212143 | 0.83 | CD38 (0.37) | LMNAMAPTSMN1; SMN2ALDH1A1HTT | |
| SCHEMBL5211936 | 0.83 | MAPT (0.42) | LMNAMAPTSMN1; SMN2MEN1POLB | |
| SCHEMBL5212052 | 0.83 | NPSR1 (0.38) | LMNAMAPTSMN1; SMN2ALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7183276-B2 | Azole compounds | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2007-02-27 | — | — | US | disclosed |
| US-20050090534-A1 | Azole compounds | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2005-04-28 | — | — | US | disclosed |
| EP-1486490-A1 | AZOLE COMPOUNDS | Takeda Chemical Industries, Ltd. (JP) | 2004-12-15 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050090534-A1 | Azole compounds | AHR, NR0B2, NR2C2 | LMNA 4253/4885L3MBTL1 3447/4885CACNA1G 3220/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.