Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 12/20 | 0.59 |
| ▸ | CYP1A1 | P04798 | 2/20 | 0.56 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | SRC | P12931 | 1/20 | 0.47 |
| ▸ | MGAM | O43451 | 1/20 | 0.46 |
| ▸ | AMY1A | P0DUB6 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | SI | P14410 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | PLOD2 | O00469 | 1/20 | 0.44 |
| ▸ | PLOD3 | O60568 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | PLOD1 | Q02809 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10362137 | 0.83 | CYP19A1 (0.61) | CYP19A1MGAMAMY1AGAASI | |
| SCHEMBL28821067 | 0.83 | CYP19A1 (0.54) | CYP19A1CYP1A1ALDH1A1 | |
| SCHEMBL8124462 | 0.81 | NOTUM (0.47) | CYP19A1 | |
| SCHEMBL4983149 | 0.77 | HTT (0.53) | HPGDSRCMGAMAMY1AGAA | |
| SCHEMBL11236728 | 0.77 | CYP19A1 (0.56) | CYP19A1CYP1A1 | |
| SCHEMBL9284133 | 0.77 | CYP19A1 (0.58) | CYP19A1CYP1A1ALDH1A1HIF1A | |
| SCHEMBL11236730 | 0.77 | CYP19A1 (0.56) | CYP19A1CYP1A1 | |
| SCHEMBL7792067 | 0.76 | ALPG (0.61) | HPGDSRCMGAMAMY1AGAA | |
| SCHEMBL11565149 | 0.76 | TP53 (0.50) | CYP19A1CYP1A1GAARAB9AALDH1A1 | |
| SCHEMBL369390 | 0.75 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025003984-A1 | INHIBITORS OF HEME OXYGENASE, COMPOSITIONS AND USES THEREOF | Università Degli Studi del Piemonte Orientale “Amedeo Avogadro” (IT) | 2025-01-02 | — | — | WO | claimed |
| EP-3250036-B1 | SMALL MOLECULE INHIBITORS OF FIBROSIS | SCRIPPS RESEARCH INST (US) | 2021-05-12 | — | — | EP | disclosed |
| US-10336735-B2 | Small molecule inhibitors of fibrosis | THE SCRIPPS RESEARCH INSTITUTE (US) | 2019-07-02 | — | — | US | disclosed |
| US-20170362211-A1 | SMALL MOLECULE INHIBITORS OF FIBROSIS | THE SCRIPPS RESEARCH INSTITUTE | 2017-12-21 | — | — | US | disclosed |
| US-20170362211-A1 | SMALL MOLECULE INHIBITORS OF FIBROSIS | THE SCRIPPS RESEARCH INSTITUTE | 2017-12-21 | — | — | US | disclosed |
| WO-2016094570-A1 | SMALL MOLECULE INHIBITORS OF FIBROSIS | THE CALIFORNIA INSTITUTE FOR BIOMEDICAL RESEARCH (US) | 2016-06-16 | — | — | WO | disclosed |
| US-20040106803-A1 | Production method of 1-substituted-1,2,3-triazole derivatives | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2004-06-03 | — | — | US | disclosed |
| US-6743924-B2 | EFFICIENT, HIGH YEILD SYNTHESIS OF TYROSINE KINASE INHIBITORS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2004-06-01 | — | — | US | disclosed |
| EP-1310491-A1 | METHOD FOR PRODUCING 1-SUBSTITUTED-1,2,3-TRIAZOLE DERIVATIVE | Takeda Chemical Industries, Ltd. (JP) | 2003-05-14 | — | — | EP | disclosed |
| US-20030069419-A1 | Method for producing 1-substituted-1,2,3- triazole derivative | TAKEDA PHARMACEUTICAL COMPANY, LIMITED (JP) | 2003-04-10 | — | — | US | disclosed |
| EP-1001947-A1 | PROCESS FOR MANUFACTURING FLUCONAZOLE | DAE WOONG PHARMACEUTICAL CO., LTD. (KR) | 2000-05-24 | — | — | EP | disclosed |
| WO-1998032744-A1 | PROCESS FOR MANUFACTURING FLUCONAZOLE | DAE WOONG PHARMACEUTICAL CO., LTD. (KR) | 1998-07-30 | — | — | WO | disclosed |
| US-5187179-A | Hypotensive agents | MERCK & CO., INC. (US) | 1993-02-16 | — | — | US | disclosed |
| EP-0505111-A2 | Angiotensin II antagonists incorporating a substituted imidazo (1,2-b)(1,2,4) triazole | MERCK & CO. INC. (US) | 1992-09-23 | — | — | EP | disclosed |
| EP-0123931-B1 | FURAN DERIVATIVES HAVING FUNGICIDE ACTIVITY | Montedison S.p.A. (IT) | 1988-12-21 | — | — | EP | disclosed |
| EP-0123931-A2 | Furan derivatives having fungicide activity | Montedison S.p.A. (IT) | 1984-11-07 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040106803-A1 | Production method of 1-substituted-1,2,3-triazole derivatives | ABL1, ROS1, ADH1A | CYP19A1 647/4885CYP1A1 216/4885HPGD 1775/4885 |
| US-20030069419-A1 | Method for producing 1-substituted-1,2,3- triazole derivative | ABL1, YES1, MAP3K1 | CYP19A1 686/4885CYP1A1 264/4885HPGD 1686/4885 |
| US-10336735-B2 | Small molecule inhibitors of fibrosis | MMP1, COL2A1, MMP8 | CYP19A1 4653/4885CYP1A1 4398/4885HPGD 1026/4885 |
| US-20170362211-A1 | SMALL MOLECULE INHIBITORS OF FIBROSIS | MMP1, COL2A1, MMP8 | CYP19A1 4653/4885CYP1A1 4398/4885HPGD 1026/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.