Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRD1 | P41143 | 12/20 | 0.54 |
| ▸ | OPRK1 | P41145 | 5/20 | 0.54 |
| ▸ | USP2 | O75604 | 1/20 | 0.47 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | OPRM1 | P35372 | 7/20 | 0.44 |
| ▸ | MLYCD | O95822 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL6139939 | 0.99 | OPRD1 (0.53) | OPRD1OPRK1USP2SMYD3HPGD | |
| SCHEMBL9482058 | 0.81 | OPRD1 (0.60) | OPRD1OPRK1OPRM1 | |
| SCHEMBL3773829 | 0.79 | MAPT (0.57) | USP2SMYD3ALDH1A1MAPTLMNA | |
| SCHEMBL14529817 | 0.78 | L3MBTL3 (0.52) | OPRD1OPRK1ALDH1A1MAPTOPRM1 | |
| SCHEMBL378149 | 0.77 | HPGD (0.54) | HPGDALDH1A1MAPTLMNA | |
| SCHEMBL7230153 | 0.77 | USP2 (0.70) | USP2SMYD3HPGDALDH1A1MAPT | |
| SCHEMBL2263367 | 0.77 | GPR119 (0.55) | USP2SMYD3HPGDALDH1A1MAPT | |
| SCHEMBL3289762 | 0.77 | SPHK1 (0.49) | OPRD1HPGDALDH1A1MAPTOPRM1 | |
| SCHEMBL3289764 | 0.77 | SPHK1 (0.49) | OPRD1HPGDALDH1A1MAPTOPRM1 | |
| Hydrochloric Acid SCHEMBL6139554 | 0.76 | HPGD (0.52) | HPGDALDH1A1MAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1242083-B1 | PHENOXYPROPANOLAMINES, METHOD FOR PRODUCING THEM AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | SANOFI AVENTIS (FR) | 2007-03-14 | — | — | EP | disclosed |
| EP-1242083-A1 | PHENOXYPROPANOLAMINES, METHOD FOR PRODUCING THEM AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | Sanofi-Aventis (FR) | 2002-09-25 | — | — | EP | disclosed |
| WO-2001043744-A1 | PHENOXYPROPANOLAMINES, METHOD FOR PRODUCING THEM AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | SANOFI-SYNTHELABO (FR) | 2001-06-21 | — | — | WO | disclosed |