SCHEMBL5208342

SCHEMBL5208342

CCC[CH]C(=O)NC(CC)CC(C)C

nearest known ligand 0.42

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
TAS1R3 Q7RTX0 5/20 0.42
TAS1R1 Q7RTX1 5/20 0.42
PLA2G10 O15496 3/20 0.38
SMN1; SMN2 Q16637 2/20 0.35
MMP8 P22894 2/20 0.32
CA12 O43570 1/20 0.32
CA1 P00915 1/20 0.32
CA2 P00918 1/20 0.32
MMP1 P03956 1/20 0.32
MMP2 P08253 1/20 0.32
CA9 Q16790 1/20 0.32
LMNA P02545 2/20 0.32
HPGD P15428 1/20 0.32
CTSK P43235 1/20 0.32
ALDH1A1 P00352 2/20 0.32
ALOX15 P16050 1/20 0.31
BIRC2 Q13490 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5209301 0.87 TAS1R3 (0.48) TAS1R3TAS1R1SMN1; SMN2MMP8CA12
SCHEMBL5209645 0.85 TAS1R3 (0.38) TAS1R3TAS1R1PLA2G10SMN1; SMN2MMP8
SCHEMBL5208329 0.79 TAS1R3 (0.38) TAS1R3TAS1R1PLA2G10SMN1; SMN2MMP8
SCHEMBL5208917 0.79 TAS1R3 (0.46) TAS1R3TAS1R1SMN1; SMN2CA1CA2
SCHEMBL8804418 0.78 TSHR (0.52) TAS1R3TAS1R1PLA2G10SMN1; SMN2MMP8
SCHEMBL5206148 0.77 MMP1 (0.44) TAS1R3TAS1R1SMN1; SMN2CA12CA1
SCHEMBL22616345 0.77 TSHR (0.48) TAS1R3TAS1R1MMP8CA12CA1
SCHEMBL4895396 0.75 TAS1R3 (0.40) TAS1R3TAS1R1ALDH1A1
SCHEMBL5203991 0.74 TAS1R3 (0.37) TAS1R3TAS1R1
SCHEMBL4889332 0.73 TAS1R3 (0.39) TAS1R3TAS1R1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0958292-B1 4-(3-HETEROCYCLYL-1-BENZOYL)PYRAZOLES AND THEIR USE AS HERBICIDES BASF AG (DE) 2007-01-03 EP disclosed
US-6165944-A 4-(3-heterocyclyl-1-benzoyl) pyrazoles and their use as herbicides BASF AKTIENGESELLSCHAFT (DE) 2000-12-26 US disclosed
EP-0958292-A1 4-(3-HETEROCYCLYL-1-BENZOYL)PYRAZOLES AND THEIR USE AS HERBICIDES BASF AKTIENGESELLSCHAFT (DE) 1999-11-24 EP disclosed
WO-1998031682-A1 4-(3-HETEROCYCLYL-1-BENZOYL)PYRAZOLES AND THEIR USE AS HERBICIDES BASF AKTIENGESELLSCHAFT (DE) 1998-07-23 WO disclosed