Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | TPSAB1 | Q15661 | 2/20 | 0.35 |
| ▸ | CACNA1B | Q00975 | 2/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.35 |
| ▸ | EGLN2 | Q96KS0 | 1/20 | 0.35 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | PSMB8 | P28062 | 1/20 | 0.34 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.34 |
| ▸ | LOX | P28300 | 2/20 | 0.34 |
| ▸ | LOXL2 | Q9Y4K0 | 2/20 | 0.34 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.33 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL5205308 | 0.94 | TPSAB1 (0.38) | TPSAB1MAPK1MEN1KMT2APSMB8 | |
| Trifluoroacetic Acid SCHEMBL5202243 | 0.92 | EPHX2 (0.36) | TPSAB1CACNA1BLOXLOXL2 | |
| Trifluoroacetic Acid SCHEMBL5208616 | 0.92 | TSPO (0.38) | TPSAB1CACNA1BMEN1KMT2APSMB8 | |
| Trifluoroacetic Acid SCHEMBL5208477 | 0.92 | ALDH1A1 (0.37) | TPSAB1CACNA1BEGLN2EGLN1MEN1 | |
| Trifluoroacetic Acid SCHEMBL5202153 | 0.91 | TSPO (0.41) | RAB9AMEN1KMT2ASCN9A | |
| Trifluoroacetic Acid SCHEMBL5205606 | 0.91 | TSPO (0.38) | MAPK1MEN1KMT2APSMB8PSMB5 | |
| Trifluoroacetic Acid SCHEMBL5204751 | 0.90 | TPSAB1 (0.35) | TPSAB1CACNA1BMAPK1MEN1KMT2A | |
| Trifluoroacetic Acid SCHEMBL5202242 | 0.90 | TPSAB1 (0.37) | TPSAB1MAPK1MEN1KMT2APSMB8 | |
| Trifluoroacetic Acid SCHEMBL5201746 | 0.89 | CACNA1B (0.36) | TPSAB1CACNA1BEGLN2EGLN1MEN1 | |
| Trifluoroacetic Acid SCHEMBL5203534 | 0.88 | KMT2A (0.37) | TPSAB1MAPK1MEN1KMT2APSMB8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7160887-B1 | Aromatic amine derivatives, their production and use | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2007-01-09 | — | — | US | disclosed |
| EP-1123918-B1 | AROMATIC AMINE DERIVATIVES, PROCESS FOR THE PREPARATION THEREOF AND AGENTS CONTAINING THE SAME | TAKEDA PHARMACEUTICAL (JP) | 2005-03-09 | — | — | EP | disclosed |
| EP-1123918-A1 | AROMATIC AMINE DERIVATIVES, PROCESS FOR THE PREPARATION THEREOF AND AGENTS CONTAINING THE SAME | Takeda Chemical Industries, Ltd. (JP) | 2001-08-16 | — | — | EP | disclosed |