Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 17/20 | 0.55 |
| ▸ | PPARG | P37231 | 17/20 | 0.55 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5209719 | 0.93 | PPARG (0.47) | PPARAPPARGPTPN1 | |
| SCHEMBL2521659 | 0.91 | PPARG (0.57) | PPARAPPARG | |
| SCHEMBL2521661 | 0.91 | PPARG (0.57) | PPARAPPARG | |
| SCHEMBL5211136 | 0.91 | PPARG (0.56) | PPARAPPARG | |
| SCHEMBL5211867 | 0.88 | PPARG (0.48) | PPARAPPARGPTPN1 | |
| SCHEMBL5210445 | 0.86 | PPARA (0.48) | PPARAPPARG | |
| SCHEMBL5206559 | 0.86 | MAPT (0.46) | PPARAPPARG | |
| SCHEMBL5205909 | 0.86 | PPARA (0.49) | PPARAPPARG | |
| SCHEMBL5210810 | 0.86 | PPARG (0.57) | PPARAPPARG | |
| SCHEMBL2518481 | 0.84 | PPARG (0.50) | PPARAPPARGPTPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1448523-B1 | HETEROCYCLIC COMPOUNDS AND METHODS OF USE | NOVARTIS AG (CH) | 2007-08-22 | — | — | EP | claimed |