Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ASAH1 | Q13510 | 6/20 | 0.52 |
| ▸ | MIF | P14174 | 4/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | CD74 | P04233 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27599848 | 0.87 | ASAH1 (0.51) | ASAH1MIFALDH1A1TP53KMT2A | |
| SCHEMBL10165252 | 0.83 | ASAH1 (0.52) | ASAH1MIFALDH1A1TP53KMT2A | |
| SCHEMBL3866731 | 0.80 | ALDH1A1 (0.64) | ASAH1ALDH1A1LMNASMN1; SMN2MAPT | |
| SCHEMBL13367743 | 0.74 | MIF (0.66) | MIFALDH1A1KMT2APOLBLMNA | |
| SCHEMBL15788594 | 0.73 | OGT (0.62) | ASAH1MIFALDH1A1TP53KMT2A | |
| SCHEMBL5302441 | 0.73 | MIF (0.63) | MIFTP53KMT2APOLBLMNA | |
| SCHEMBL1025445 | 0.72 | PKM (0.58) | MIFALDH1A1KMT2APOLBLMNA | |
| SCHEMBL16601597 | 0.72 | HPGD (0.64) | MIFTP53KMT2ASMN1; SMN2CD74 | |
| SCHEMBL5286912 | 0.70 | MIF (0.53) | ASAH1MIFALDH1A1TP53KMT2A | |
| SCHEMBL16366708 | 0.70 | ASAH1 (0.56) | ASAH1ALDH1A1TP53KMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1363925-B8 | MACROLIDE ANTIBIOTICS | GLAXO GROUP LTD (GB) | 2007-04-25 | — | — | EP | disclosed |
| EP-1363925-A1 | MACROLIDE ANTIBIOTICS | GLAXO GROUP LIMITED (GB) | 2003-11-26 | — | — | EP | disclosed |
| WO-2002050091-A1 | MACROLIDE ANTIBIOTICS | GLAXO GROUP LIMITED (GB) | 2002-06-27 | — | — | WO | disclosed |