Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | MTNR1A | P48039 | 4/20 | 0.36 |
| ▸ | MTNR1B | P49286 | 4/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.35 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.33 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.33 |
| ▸ | RELA | Q04206 | 1/20 | 0.33 |
| ▸ | GRM6 | O15303 | 1/20 | 0.33 |
| ▸ | F11 | P03951 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.32 |
| ▸ | STING1 | Q86WV6 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5623315 | 0.81 | CYP2C9 (0.37) | USP2CYP3A4MAPK1SMN1; SMN2MTNR1A | |
| SCHEMBL5236558 | 0.77 | MTNR1A (0.42) | USP2CYP3A4MAPK1SMN1; SMN2MTNR1A | |
| SCHEMBL29097074 | 0.76 | CYP3A4 (0.63) | USP2CYP3A4MAPK1SMN1; SMN2KMT2A | |
| SCHEMBL21591091 | 0.72 | CYP3A4 (0.41) | USP2CYP3A4MAPK1SMN1; SMN2MTNR1A | |
| SCHEMBL5203894 | 0.72 | CYP3A4 (0.38) | USP2CYP3A4MAPK1SMN1; SMN2KMT2A | |
| SCHEMBL28465659 | 0.72 | ALDH1A1 (0.49) | SMN1; SMN2KMT2AKDM4ENPSR1ABCB1 | |
| SCHEMBL31313234 | 0.72 | KDM4E (0.32) | MAPK1SMN1; SMN2MTNR1AMTNR1BKMT2A | |
| SCHEMBL21591073 | 0.71 | MTNR1A (0.41) | MAPK1SMN1; SMN2MTNR1AMTNR1BKMT2A | |
| SCHEMBL21591042 | 0.71 | MTNR1A (0.36) | MAPK1SMN1; SMN2MTNR1AMTNR1BKMT2A | |
| SCHEMBL20987104 | 0.70 | ELANE (0.50) | MAPK1ABCG2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1403250-B1 | BIS(5-ARYL-2-PYRIDYL) DERIVATIVE | KOWA CO (JP) | 2007-07-18 | — | — | EP | disclosed |
| EP-1403251-B1 | BIS(2-ARYL-5-PYRIDYL) DERIVATIVE | KOWA CO (JP) | 2007-07-18 | — | — | EP | disclosed |
| EP-1403250-A1 | BIS(5-ARYL-2-PYRIDYL) DERIVATIVE | Kowa Co., Ltd. (JP) | 2004-03-31 | — | — | EP | disclosed |
| EP-1403251-A1 | BIS(2-ARYL-5-PYRIDYL) DERIVATIVE | Kowa Co., Ltd. (JP) | 2004-03-31 | — | — | EP | disclosed |