SCHEMBL5208730

SCHEMBL5208730

[CH2]CC(CCCC(C)C(=O)OC(C)C)C(=O)OCCCC

nearest known ligand 0.36

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.36
TSHR P16473 3/20 0.36
HPGD P15428 1/20 0.36
CA1 P00915 3/20 0.35
LMNA P02545 2/20 0.35
CA2 P00918 2/20 0.35
ATM Q13315 1/20 0.34
MAPT P10636 1/20 0.33
NPSR1 Q6W5P4 1/20 0.33
BIRC2 Q13490 1/20 0.32
HCAR2 Q8TDS4 1/20 0.31
MAPK1 P28482 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7684082 0.78 ALDH1A1 (0.39) ALDH1A1TSHRHPGDCA1LMNA
SCHEMBL6900329 0.78 LMNA (0.48) ALDH1A1TSHRCA1LMNACA2
SCHEMBL7223143 0.76 CA1 (0.55) CA1LMNA
SCHEMBL27533711 0.75 ALDH1A1 (0.45) ALDH1A1TSHRHPGDCA1LMNA
SCHEMBL28311582 0.74 LMNA (0.55) CA1LMNA
SCHEMBL7218183 0.74 LMNA (0.55) CA1LMNA
Hydrochloric Acid SCHEMBL28164871 0.74 CA1 (0.53) CA1LMNA
SCHEMBL8046834 0.74 LMNA (0.47) ALDH1A1TSHRLMNAATMMAPT
SCHEMBL5458029 0.74 ALDH1A1 (0.52) ALDH1A1TSHRHPGDCA1LMNA
SCHEMBL18859460 0.74 ALDH1A1 (0.52) ALDH1A1TSHRHPGDCA1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0958292-B1 4-(3-HETEROCYCLYL-1-BENZOYL)PYRAZOLES AND THEIR USE AS HERBICIDES BASF AG (DE) 2007-01-03 EP disclosed