Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | DGKA | P23743 | 1/20 | 0.46 |
| ▸ | NAAA | Q02083 | 1/20 | 0.42 |
| ▸ | HTR2C | P28335 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | ATM | Q13315 | 2/20 | 0.39 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.38 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.38 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28143492 | 0.88 | DGKA (0.50) | DGKANAAAHTR2CALDH1A1MAPT | |
| SCHEMBL18915710 | 0.86 | DGKA (0.42) | LMNADGKANAAAHTR2CALDH1A1 | |
| SCHEMBL8268189 | 0.85 | DGKA (0.47) | DGKANAAAHTR2CALDH1A1MAPT | |
| SCHEMBL29761942 | 0.82 | LMNA (0.63) | LMNADGKANAAAHTR2CALDH1A1 | |
| SCHEMBL11329144 | 0.82 | MAPT (0.53) | LMNADGKANAAAHTR2CALDH1A1 | |
| SCHEMBL14712672 | 0.81 | NAAA (0.56) | LMNADGKANAAAHTR2CALDH1A1 | |
| SCHEMBL29094046 | 0.81 | LMNA (0.72) | LMNADGKANAAAALDH1A1MAPT | |
| SCHEMBL29779779 | 0.81 | LMNA (0.61) | LMNADGKANAAAHTR2CALDH1A1 | |
| SCHEMBL127529 | 0.80 | DGKA (0.53) | LMNADGKANAAAHTR2CALDH1A1 | |
| SCHEMBL7933773 | 0.80 | LMNA (0.48) | LMNAALDH1A1MAPTTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6077953-A | INTERMEDIATES TO PRODUCE PYRIDAZIN-3-ONE COMPOUNDS WHICH ARE HERBICIDAL COMPOUNDS. | SUMITOMO CHEMICAL CO., LTD. (JP) | 2000-06-20 | — | — | US | disclosed |