SCHEMBL5208922

SCHEMBL5208922

[CH2]CCCC(=O)N(CCC)CCCC

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.50
HPGD P15428 1/20 0.50
MMP1 P03956 1/20 0.46
MMP2 P08253 1/20 0.46
MMP3 P08254 1/20 0.46
MMP8 P22894 1/20 0.46
SIGMAR1 Q99720 2/20 0.45
CA12 O43570 3/20 0.44
CA9 Q16790 3/20 0.44
CA1 P00915 2/20 0.44
LMNA P02545 1/20 0.43
HDAC3 O15379 1/20 0.41
HDAC1 Q13547 1/20 0.41
HDAC2 Q92769 1/20 0.41
HDAC6 Q9UBN7 1/20 0.41
NCOR2 Q9Y618 1/20 0.41
KDM5A P29375 4/20 0.38
KDM4C Q9H3R0 3/20 0.38
CA2 P00918 1/20 0.38
PHF8 Q9UPP1 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5206232 0.96 MMP1 (0.48) ALDH1A1HPGDMMP1MMP2MMP3
SCHEMBL5207277 0.94 ALDH1A1 (0.55) ALDH1A1HPGDMMP1MMP2MMP3
SCHEMBL5208148 0.90 ALDH1A1 (0.52) ALDH1A1HPGDMMP1MMP2MMP3
SCHEMBL5208505 0.89 LMNA (0.54) ALDH1A1HPGDMMP1MMP2MMP3
SCHEMBL5209308 0.86 LMNA (0.56) ALDH1A1HPGDMMP1MMP2MMP3
SCHEMBL18106520 0.86 ALDH1A1 (0.52) ALDH1A1HPGDCA12CA9LMNA
SCHEMBL2046999 0.86 MMP1 (0.50) ALDH1A1HPGDMMP1MMP2MMP3
SCHEMBL23044060 0.84 ALDH1A1 (0.53) ALDH1A1HPGDMMP1MMP2MMP3
SCHEMBL28987951 0.84 ALDH1A1 (0.53) ALDH1A1HPGDMMP1MMP2MMP3
SCHEMBL29174019 0.84 ALDH1A1 (0.53) ALDH1A1HPGDMMP1MMP2MMP3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0958292-B1 4-(3-HETEROCYCLYL-1-BENZOYL)PYRAZOLES AND THEIR USE AS HERBICIDES BASF AG (DE) 2007-01-03 EP disclosed
US-6165944-A 4-(3-heterocyclyl-1-benzoyl) pyrazoles and their use as herbicides BASF AKTIENGESELLSCHAFT (DE) 2000-12-26 US disclosed
EP-0958292-A1 4-(3-HETEROCYCLYL-1-BENZOYL)PYRAZOLES AND THEIR USE AS HERBICIDES BASF AKTIENGESELLSCHAFT (DE) 1999-11-24 EP disclosed
WO-1998031682-A1 4-(3-HETEROCYCLYL-1-BENZOYL)PYRAZOLES AND THEIR USE AS HERBICIDES BASF AKTIENGESELLSCHAFT (DE) 1998-07-23 WO disclosed