SCHEMBL5208933

SCHEMBL5208933

OCC1CSC(c2ccccc2-c2ccccc2C2SCC(CO)S2)S1

nearest known ligand 0.56

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.34
POLB P06746 1/20 0.34
HPGD P15428 1/20 0.34
HTR2A P28223 2/20 0.33
HTR2B P41595 1/20 0.33
TDO2 P48775 1/20 0.33
CYP1A2 P05177 1/20 0.33
TSHR P16473 1/20 0.33
MAPT P10636 1/20 0.32
MEN1 O00255 1/20 0.31
KMT2A Q03164 1/20 0.31
HDAC3 O15379 1/20 0.30
HDAC4 P56524 1/20 0.30
HDAC7 Q8WUI4 1/20 0.30
HDAC8 Q9BY41 1/20 0.30
HDAC6 Q9UBN7 1/20 0.30
HDAC9 Q9UKV0 1/20 0.30
HDAC5 Q9UQL6 1/20 0.30
NCOR2 Q9Y618 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28748700 0.92 ALDH1A1 (0.35) ALDH1A1POLBHPGD
SCHEMBL5213356 0.91 ALDH1A1 (0.30) ALDH1A1POLBHPGDMAPTMEN1
SCHEMBL11795447 0.85 MEN1 (0.43) ALDH1A1HTR2AHTR2BTSHRMAPT
SCHEMBL5209567 0.83 HTR2A (0.33) HTR2A
SCHEMBL5205512 0.82 HTR1A (0.36) MAPTMEN1KMT2A
SCHEMBL5207532 0.81 HTR2C (0.30) HTR2B
SCHEMBL6862831 0.81 KDM1A (0.39) CYP1A2MAPTHDAC3HDAC8NCOR2
SCHEMBL6862816 0.79 SLC18A3 (0.34) ALDH1A1
SCHEMBL5212503 0.76 GABRP (0.37) ALDH1A1
SCHEMBL11792377 0.74 ALDH1A1 (0.30) ALDH1A1POLBHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1388540-B1 ACRYLIC ESTERS AND USE THEREOF MITSUI CHEMICALS INC (JP) 2007-09-05 EP disclosed
EP-1388540-A1 ACRYLIC ESTERS AND USE THEREOF Mitsui Chemicals, Inc. (JP) 2004-02-11 EP disclosed